Influence of Coffee Intake on Postoperative Bowel Function After Comprehensive Staging Surgery for Gynecological Malignancies: A Randomized Controlled Trial.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 118
- 试验地点
- 2
- 主要终点
- time to first flatus
研究概览
简要总结
A delay in the return of normal bowel function with the passage of flatus and feces is one of the most important factors affecting early recovery and discharge in patients undergoing open complete staging surgery for gynecological malignancies. A prolonged hospital stay increases the risk of hospital-acquired infections, deep vein thrombosis, pulmonary compromise and total hospital costs.
The aim of this study was to assess the effectiveness of coffee intake on postoperative bowel function in patients undergoing abdominal complete staging surgery for gynecological malignancies.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Female patients preparing for complete surgical staging for malignant gynecologic disease such as endometrial cancer, cervix cancer and ovarian cancerwere assessed for eligibility.
排除标准
- •Exclusion criteria for the study
- •included thyroid diseases,
- •inflammatory bowel disease,
- •complaints of chronic constipation (defined as two or fewer bowel movements per week),
- •a history of prior abdominal bowel surgery, abdominal radiation, neoadjuvant chemotherapy,
- •need for intensive care more that 24 hpostoperatively,
- •nasogastric tube drainage beyond the first postoperative morning,
- •bowel anastomosis and upper abdominalmultivisceral surgical approaches in relation to the debulking surgery.
结局指标
主要结局
time to first flatus
时间窗: within the first 30 days after surgery
hours from end of operation to first flatus pass time
次要结局
- time to tolerance diet(within the first 30 days after surgery)
研究者
Kemal GUNGORDUK
Medical Doctor
Erzincan Military Hospital