Wound Healing Abnormalities in Major Abdominal Surgery

Completed

• Conditions: Impaired Wound Healing; Factor XIII Deficiency

• Registration Number: NCT00735579
• Lead Sponsor: Klinikum St. Georg gGmbH

Brief Summary

This clinical observational study investigates the incidence of wound healing abnormalities in patients undergoing major abdominal surgery. Second aim of the study is, if wound healing deficits may be accompanied by abnormalities in blood coagulation parameters.

Detailed Description

Not available

Study Timeline

• Study Start: 2008-07
• Study First Submitted: 2008-08-14
• Study First Submitted QC: 2008-08-14
• Study First Posted: 2008-08-15
• Status Verified: 2017-04
• Primary Completion: 2017-04-21
• Study Completion: 2017-04-21
• Last Update Submitted: 2017-04-21
• Last Update Posted: 2017-04-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 260

Inclusion Criteria

• Age >= 18 years
• Male or female
• Informed consent
• Major abdominal surgery

Exclusion Criteria

• Pre-existing coagulation abnormalities
• Pre-existing severe renal or liver failure
• Chemo- or radiochemotherapy

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Incidence of wound healing abnormalities	from baseline to postoperative day 28	Occurence of wound healing abnormalities within the first 28 days after surgery

Secondary Outcome Measures

Name	Time	Method
Abnormalities in coagulation parameters	postoperative day 28	occurence of low platelets (\<60.000) or factor XIII \< 50% between the first and seventh postoperative day

Trial Locations

Locations (1)

Klinikum St. Georg gGmbH; 🇩🇪 Leipzig, Sachsen, Germany