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Comparison of the PaO2/FiO2 Ratio to Other Oxygenation Indexes for the Classification of Severity of Acute Respiratory Distress Syndrome

Completed
Conditions
Acute Respiratory Distress Syndrome
Interventions
Diagnostic Test: Obtaining arterial blood gases
Registration Number
NCT03946189
Lead Sponsor
American University of Beirut Medical Center
Brief Summary

In mechanically ventilated patients the PaO2/FiO2 ratio might not be the best reflection of the severity of ARDS. It does not incorporate variables and settings used during mechanical ventilatory support such as the positive end expiratory pressure (PEEP), inspiratory time to expiratory time ratio (Ti:Te), and the peak alveolar pressure (Palv). The aim is to identify a new oxygenation index for stratification of severity of ARDS

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
150
Inclusion Criteria
  • Patients receiving mechanical ventilation in the Intensive Care Unit.
  • Patients in whom the managing medical team requested an arterial blood gas (ABG) analysis.
Exclusion Criteria
  • Patients in whom arterial blood gas could not be obtained or not ordered.

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
P/F less than 100Obtaining arterial blood gasesPatients receiving mechanical ventilation with paO2/FiO2 less than 100
P/F between 100 and 200Obtaining arterial blood gasesPatients receiving mechanical ventilation with paO2/FiO2 between 100 and 200
P/F between 200-300Obtaining arterial blood gasesPatients receiving mechanical ventilation with paO2/FiO2 between 200 and 300
Primary Outcome Measures
NameTimeMethod
New oxygenation indexImmediate

Oxygenation index that incorporates ventilator parameters

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

American University of Beirut

🇱🇧

Beirut, Lebanon

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