NCT00140894终止4 期
A Randomized, Double-Blind, Placebo-Controlled Study to Assess the Safety and Efficacy of Rofecoxib in Familial Adenomatous Polyposis (FAP)
适应症
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 终止
- 入组人数
- 62
- 主要终点
- Number and average size of rectal polyps
研究概览
简要总结
A study to evaluate rofecoxib in the treatment of rectal, colon, or duodenal adenomas in patients with Familial Adenomatous Polyposis.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Males or females at least 18 years of age with familial adenomatous polyposis.
排除标准
- 未提供
结局指标
主要结局
Number and average size of rectal polyps
Safety and tolerability
次要结局
- Number and average size of duodenal polyps
- Proportions of patients with improved overall colon rating
研究者
相似试验
终止
4 期
A Double-blind, Double-dummy, Multicenter, Randomized Study of the Efficacy and Tolerability of Valdecoxib 40 mg Versus Rofecoxib 50 mg in Treating the Symptoms of Ankle SprainAcute PainNCT00657449Pfizer45
终止
3 期
A Study to Evaluate Rofecoxib Versus Placebo and Diclofenac in Patients With Acute Painful Rotator Cuff SyndromePainNCT00140933Merck Sharp & Dohme LLC274
已完成
3 期
Effect of Rofecoxib and a Narcotic Analgesic to Treat Pain Following Arthroscopic Surgery (0966-179)(COMPLETED)Pain, Postoperative ArthroscopyNCT00390260Merck Sharp & Dohme LLC420
进行中（未招募）
3 期
A Study to Evaluate the Efficacy and Safety of Rozanolixizumab in Adult Participants With Myelin Oligodendrocyte Glycoprotein (MOG) Antibody-associated Disease (MOGAD)Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease (MOG-AD)NCT05063162UCB Biopharma SRL113
已完成
2 期
Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study In Subjects With Osteoarthritic Pain Of The KneeOsteoarthritis, KneeNCT00689273Pfizer159