Treatment of Covid-19 patients with convalescent plasma
Phase 3
Recruiting
- Conditions
- COVID-19 disease.
- Registration Number
- IRCT20200525047562N1
- Lead Sponsor
- High Educational and Research Institute of Transfusion Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
Symptomatic COVID-19 patients who are hospitalized and have Score>4 in terms of WHO Progression Scale.
The least reasons of hospitalization are dyspnea and/or SPO2<93% or RR>30
The intervention should be performed within the first 24 hours of hospitalization.
Exclusion Criteria
COVID-19 patients having Score<4 in terms of WHO Progression Scale.
More than 24 hours passed from hospitalization.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Reduce at least 2 points on clinical signs or score less than 3, each earlier. Timepoint: At the beginning of the study (before the start of the intervention) and day 4 of hospitalization, day 7 of hospitalization and discharge time. Method of measurement: WHO Progression Scale.;Length of hospital stay. Timepoint: Hospitalization time to discharge. Method of measurement: Counting days.
- Secondary Outcome Measures
Name Time Method The rate of need for artificial ventilation and entry into the ICU. Timepoint: From hospitalization to discharge. Method of measurement: Percentage calculation.