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Clinical Trials/NCT07455370
NCT07455370Enrolling By InvitationNot Applicable

Moral Distress, Moral Injury and Post-Traumatic Stress Among Mayo Clinic Nurses

Mayo Clinic3 sites in 1 country21,300 target enrollmentStarted: March 3, 2026Last updated:
Interventions

Trial Snapshot

Phase
Not Applicable
Status
Enrolling By Invitation
Enrollment
21,300
Locations
3
Primary Endpoint
Measure of Moral Distress-Healthcare Professionals (MMD-HP) Score

Study Overview

Brief Summary

The goal of this descriptive study is to examine levels of moral distress (MD), moral injury (MI), & post-traumatic stress (PTS) levels among nursing staff at Mayo Clinic. The main questions this study aims to answer are:

  1. Determine the levels of MD, MI, and PTS symptoms experienced by nurses who participate in the study.
  2. Evaluate differences in MD, MI, and PTS symptoms by setting, specialties, and geographic locations.
  3. Examine demographic and professional characteristics that are associated with high levels of MD, MI and PTS.

Study Design

Study Type
Observational
Observational Model
Case Only
Time Perspective
Cross Sectional

Eligibility Criteria

Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Mayo Clinic Department of Nursing Staff including:
  • Registered nurses
  • Licensed practical nurses
  • Nursing support staff (including roles such as patient care assistants, patient care specialists, medical assistants, and nurse technicians)

Exclusion Criteria

  • Social workers
  • Chaplains
  • Unit coordinators
  • Other staff who do not support direct patient care but are within the nursing department
  • Other employees outside the Department of Nursing

Arms & Interventions

Mayo Clinic Nurses

Mayo Clinic Department of Nursing staff across the enterprise including advanced practice nurses, registered nurses, licensed practical nurses, and nursing support/unlicensed staff.

Intervention: Surveys (Other)

Outcomes

Primary Outcomes

Measure of Moral Distress-Healthcare Professionals (MMD-HP) Score

Time Frame: Baseline

The MMD-HP (Measure of Moral Distress-Healthcare Professionals) is a 27-item moral distress scale. A composite score is computed for items 1 - 25 and is obtained by multiplying the frequency scores (0 = Never to 4 = Very Frequently scale) and the distress scores (0 = None to 4 = Very Distressing scale) for each item; the products of these can range from 0 - 16. Higher scores indicate a greater deal of moral distress.

Moral Injury Outcome Scale (MIOS) score

Time Frame: Baseline

The Moral Injury Outcome Scale (MIOS) is a 14-item self-reported survey divided into two subscales-shame-related and trust-violation related. Both the shame and trust-violated subscales are seven items per subscale. Respondents are asked to indicate how strongly they agree with each statement in the past month using a 5 point Likert scale where 0 = Strongly Disagree and 4 = Strongly Agree. The total score range for each subscale is 0 - 28, and the overall score range is 0 - 56. Symptom severity is categorized as follows: 14 - 28 indicates mild moral injury, 29 - 42 indicates moderate moral injury, and 35 - 56 indicates severe moral injury.

Post-Traumatic Stress Disorder (PCL-5) score

Time Frame: Baseline

The PCL - 5 (Post-Traumatic Stress Disorder (PSTD) Checklist) is a 20-item self-reported survey that assesses the 20 DSM-5 symptoms of PTSD. Respondents are asked to indicate the frequency that each item occurs on a 5 point Likert scale where 0 = Not at All and 4 = Extremely. The total score is the sum of all 20 questions, with higher scores indicating a greater likelihood of PTSD.

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Melissa A. Wilson

Senior Associate Consultant

Mayo Clinic

Study Sites (3)

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