Comparison of Exercise Capacity, Muscle Parameters and Quality of Life Parameters in Chronic Obstructive Pulmonary Disease Patients and Healthy Individuals
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Cardiopulmonary exercise test
研究概览
简要总结
The investigators think that the functions of core stabilization muscles are different in chronic obstructive pulmonary disease (COPD) patients than in healthy individuals. This muscle group plays an important role not only in stabilization but also in respiratory parameters. No study has been found investigating the functions of these muscles in this patient group. The investigators aimed to compare respiratory parameters, muscle parameters, exercise capacity, balance, quality of life, anxiety and depression levels in individuals with COPD and healthy individuals.
详细描述
Individuals diagnosed with COPD between the ages of 40-80 who applied to Ankara Etlik City Hospital Chest Diseases Polyclinic will be included in the study. Healthy individuals will be between the ages of 40-80 who volunteered to participate in the study. Data collection tools will be made by the same researchers.
For calculating the sample size required for the study, a power analysis will be conducted using pilot data after evaluating 10 individuals with COPD and 10 healthy adults.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 40 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Inclusion Criteria for Individuals with COPD:
- •Being diagnosed with COPD
- •Being between the ages of 40-80
- •Being clinically stable (not having had an exacerbation in the last month)
- •Being able to cooperate with the tests
- •Not participating in any exercise training studies
- •Being willing to participate in the study
- •Inclusion Criteria for Healthy Individuals:
- •Being between the ages of 40-80
- •Not having a known acute or chronic health problem that would prevent the performance of the tests or affect the performance of the tests
- •Not participating in any exercise training program
- •Being willing to participate in the study
排除标准
- •Exclusion Criteria for Individuals with COPD:
- •Having other lung or lung involvement diseases other than COPD
- •Having uncontrolled hypertension, arrhythmia and a history of myocardial infarction in the last month, unstable angina, advanced heart failure and other cardiac instability conditions
- •Being hemodynamically unstable
- •Being on noninvasive mechanical ventilation (NIMV) and long-term oxygen therapy (LTOT)
- •Having a history of neuromuscular disease, scoliosis, chest wall surgery
- •Having pregnancy and malignancy
- •Having orthopedic or surgical conditions that would prevent participation in tests
- •Not willing to participate in the study
- •Exclusion Criteria for Healthy Individuals:
- •Having a known acute or chronic health problem that would prevent the performance of the tests or affect the performance of the tests
- •Being pregnant
- •Not willing to participate in the study
结局指标
主要结局
Cardiopulmonary exercise test
时间窗: September 2024, July 2026
Cardiopulmonary exercise test will be performed to evaluate the exercise capacity of the individuals who will participate in the study. During the test, individuals' respiratory and cardiac parameters will be recorded.
次要结局
- Respiratory function(September 2024, July 2026)
- Respiratory muscle strength(September 2024, July 2026)
- Functional reach test(September 2024, July 2026)
- Muscle activity and muscle thickness(September 2024, July 2026)
- COPD Assessment Questionnaire(September 2024, July 2026)
- Timed up and go test(September 2024, July 2026)
- St George Health Questionnaire(September 2024, July 2026)
- Hospital Anxiety and Depression Scale(September 2024, July 2026)
- Six Minute Walk Test (6MWT)(September 2024- July 2026)
研究者
Elif Cansu Özkılıçaslan
Physiotherapist, M.Sc
Hacettepe University