The effect of N-acetyl cysteine on renal function after open heart surgery

Phase 3

• Conditions: kidney disease.; Hypertensive heart and chronic kidney disease

• Registration Number: IRCT20190506043492N3
• Lead Sponsor: Ahvaz University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 15 June 2020

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Candidates for open heart surgery.
Be 30 to 70 years old.
Have normal kidney and liver functionDo not have thyroid disease, hypertension, diabetes and arrhythmia.
Don't be addicted to drugs.
Glomerular filtration should be less than 60.

Exclusion Criteria

The patient is not satisfied to participate in the study.
If the patient is taking renal effective drugs such as steroids and anti-inflammatory.
If you are allergic to N-acetyl cysteine.

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The effect of N-acetyl cysteine on renal factors after open heart surgery. Timepoint: Before anesthesia, 1,3,12, 24 and 48 hours later. Method of measurement: Serum level of creatinine in blood tests.;The effect of N-acetyl cysteine on renal factors after open heart surgery. Timepoint: Before anesthesia, 1,3,12, 24 and 48 hours later. Method of measurement: Serum level of BUN in blood tests.;The effect of N-acetyl cysteine on renal factors after open heart surgery. Timepoint: Before anesthesia, 1,3,12, 24 and 48 hours later. Method of measurement: Serum level of GFR in blood tests.;The effect of N-acetyl cysteine on renal factors after open heart surgery. Timepoint: Before anesthesia, 1,3,12, 24 and 48 hours later. Method of measurement: Urinary albumin levels.