Effects of Resistance and Endurance Training in Pediatric Cancer Patients During Intensive Treatment Phase
Not Applicable
Completed
- Conditions
- Pediatric Oncology
- Interventions
- Behavioral: Exercise Training
- Registration Number
- NCT02612025
- Lead Sponsor
- Johannes Gutenberg University Mainz
- Brief Summary
The purpose of this study is to determine whether combined endurance and resistance training can improve muscle strength in children and adolescents with cancer during the intensive treatment phase.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 35
Inclusion Criteria
- Malignant Tumor
- Medical Treatment in the Center for Pediatrics, Hematology, Oncology and Hemostaseology Mainz (Germany)
- > 3 years
- Signed Informed Consent
Exclusion Criteria
- Functional and/or cognitive limitations which limit performance during training
- Orthopedic condition which hinders to adequately participate in exercise training
- Heart failure (NYHA III-IV)
- Partial or global respiratory failure
- Symptomatic coronary disease
- Serious therapy-refractory hypertonia
- Sustainable thrombocytopenia <10.000/µl, f. ex. therapy-refractory autoimmune thrombocytopenia
- Hereditary or acquired thrombocytopenia or coagulation disturbance
- Uncontrolled cerebral spasm
- CNS metastases
- Medical or psychological condition which does in the doctors opinion not allow participation in sport activity
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Exercise group Exercise Training Exercise training during intensive medical treatment
- Primary Outcome Measures
Name Time Method Muscle strength: lower limb Six weeks (pre-post intervention) Lower limb muscle strength measured by the load (kg) sustained in one repetition maximum test
- Secondary Outcome Measures
Name Time Method Six-minute-walk performance Six weeks (pre-post intervention) Muscle strength: upper limb Six weeks (pre-post intervention) Upper limb muscle strength measured by the load (kg) sustained in one repetition maximum test
Body composition Six weeks (pre-post intervention) Bioelectrical Impedance Analysis
Fatigue six weeks (pre-post intervention) Pediatric Quality of Life Inventory (PedsQL) Multidimensional Fatigue Scale
Biomarker in Blood At the beginning of the intervention and three and six weeks after the beginning. Comparing the two time points inbetween study groups Immune status and metabolic status
Quality of Life Six weeks (pre-post intervention) KINDL: health related quality of life questionnaire
Cardiorespiratory performance Six weeks (pre-post intervention) Ergospirometry
Trial Locations
- Locations (1)
Johannes-Gutenberg-University
🇩🇪Mainz, Rhineland-Palatinate, Germany