Effects of Ketamine On Precipitated Opioid Withdrawal Under General Anaesthesia

Phase 4

Completed

• Conditions: Opiate Dependence

• Registration Number: NCT00300794
• Lead Sponsor: Vilnius University

Brief Summary

The purpose of this study is to determine whether low-dose ketamine infusion is effective in suppressing the symptoms of opiate withdrawal during rapid opiate antagonist induction (RAI).

Detailed Description

Not available

Study Timeline

• Study Start: 2003-02
• Study First Submitted: 2006-03-07
• Study First Submitted QC: 2006-03-07
• Study First Posted: 2006-03-09
• Study Completion: 2006-06
• Status Verified: 2006-11
• Last Update Submitted: 2006-11-13
• Last Update Posted: 2006-11-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Diagnosed opiate dependence according to ICD 10 and/or DSM 4;
• Duration of substance abuse more than 1 year
• No or minor co-morbidities;
• Grade I-II according to physical status classification system of American Society of Anesthesiologists.

Exclusion Criteria

• Current history of long acting opiate or poly-substance abuse;
• Acute medical or surgical condition;
• Pregnancy;
• Breastfeeding.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Trial Locations

Locations (1)

Vilnius University Emergency Hospital; 🇱🇹 Vilnius, Lithuania