Fluctuation of the renal function after discharge from hospital and its effects on drug dosing in elderly patients.
Recruiting
- Conditions
- kidney functionRenal function10038430
- Registration Number
- NL-OMON43767
- Lead Sponsor
- Jeroen Bosch Ziekenhuis
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 129
Inclusion Criteria
age >= 70 years,
renal function < 60 ml/min/1.73m2
Exclusion Criteria
Patients on dialysis
Patients in their terminal phase
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The main study parameter is the estimated glomerular filtration rate (eGFR).<br /><br>The main endpoint is: 1) What percentage of patients show improved,<br /><br>deteriorated and unchanged renal function at 14 days after discharge from<br /><br>hospital compared to the renal function at discharge? Renal function will be<br /><br>classified according the categories, which are defined in relation to drug<br /><br>management. </p><br>
- Secondary Outcome Measures
Name Time Method <p>Other important endpoints are:<br /><br>1) What percentage of patients show improved, deteriorated and unchanged renal<br /><br>function at 2 months after discharge from hospital compared to the renal<br /><br>function at discharge?<br /><br>2) Percentage of patients whose actual medications are incorrect according to<br /><br>the Dutch guidelines in relation to their renal function at 14 days and 2<br /><br>months after discharge.<br /><br>3) Percentage of patients in whom fluctuation of the renal function would have<br /><br>required dose adaptation of a hypothetical selection of drugs at 14 days and 2<br /><br>months after discharge.</p><br>