Can six months consumption of daun kesum supplement improve memory, mood and brain function among older adults with memory impairment?

Not Applicable

Completed

• Conditions: Mild cognitive impairment; Mental and Behavioural Disorders; Mild cognitive disorder

• Registration Number: ISRCTN12417552
• Lead Sponsor: Biotropics Malaysia Berhad

Brief Summary

2020 Results article in https://pubmed.ncbi.nlm.nih.gov/33076878/ (added 07/09/2021)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2018-09-15
• Study Start: 2019-08-30
• Last Update Posted: 20 September 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 36

Inclusion Criteria

1. Malaysian older adults age between 60-75 years at the time of informed consent
2. BMI between 20-30 kg/m2
3. MCI based on Peterson criteria

Exclusion Criteria

1. Alcohol and/or substance dependence
2. Had any type of neurodegenerative diseases (i.e. Parkinson disease, Alzheimer’s disease, dementia)
3. Had a diagnosis of a depressive disorder, schizophrenia or score > 5 in Geriatric Depression Scale (GDS)
4. Had any medical conditions might interfere with the subject’s participation in the trial (i.e. serious diabetes, chronic heart disease, cancer and kidney, liver or renal failure
5. Had Attention Deficit Hyperactivity Disorder (ADHD). These conditions might interfere with the outcome such as cognition function and psychosocial status
6. Regular consumer of traditional herbs, vitamin and mineral supplementation for the past six months because it will jeopardize the effect of supplement used in the study
7. Had a metallic implant, such as prostheses, shrapnel or aneurysm clips, or electronic implants, such as cardiac pacemakers
8. Claustrophobic
9. On Hormone Replacement Therapy (HRT)

Study & Design

• Study Type: Interventional
• Study Design: Not specified