Real-time Navigation for Laparoscope Liver Resections Using Fusion 3D Imaging and Indocyanine Green Fluorescence Imaging
Overview
- Phase
- Phase 2
- Intervention
- Laparoscopic surgical navigation system
- Conditions
- Liver Resection
- Sponsor
- Zhujiang Hospital
- Enrollment
- 50
- Locations
- 1
- Primary Endpoint
- Liver resection navigation success rate
- Last Updated
- 7 years ago
Overview
Brief Summary
The aim of this study was to evaluate the feasibility and efficacy of a novel real-time navigation way for laparoscope liver resection, which was fused images comprising 3D imaging and indocyanine green Fluorescence imaging (fusion IGFI).
Detailed Description
During liver resection, surgeons cannot completely view the intraparenchymal structure. Although a fluorescent imaging technique using indocyanine green has recently been developed for hepatobiliary surgery, limitations in its application for real-time navigation persist. A nove augmented reality surgery navigation system (ARSNS) can be combined with indocyanine green Fluorescence imaging to guide the surgery real-time.
Investigators
Eligibility Criteria
Inclusion Criteria
- •18 years≤ Age ≤70 years
- •Compling with the diagnosis criteria of complex hepatic carcinoma.
- •Primary hepatic carcinoma without intrahepatic or extrahepatic extensive cancer metastasis, the metastatic hepatic carcinoma whose primary focal has been controlled
- •Preoperative liver function is Child - Pugh grade A or B.
- •The patients are volunteered for the study.
Exclusion Criteria
- •Patients with mental illness.
- •Patients can't tolerate the operation owe to a variety of basic diseases (such as severe cardiopulmonary insufficiency, renal insufficiency, cachexia and blood system diseases, etc.)
- •The patients refused to take part in the study.
- •There are other co-existed malignant tumors.
- •Benign liver diseases.
- •Indocyanine green allergy
Arms & Interventions
Experimental group
Hepatectomy procedures were performed under Laparoscopic surgical navigation system and Indocyanine Green guidance.
Intervention: Laparoscopic surgical navigation system
Experimental group
Hepatectomy procedures were performed under Laparoscopic surgical navigation system and Indocyanine Green guidance.
Intervention: Indocyanine Green
Outcomes
Primary Outcomes
Liver resection navigation success rate
Time Frame: intraoperative
Whether this technique successfully displayed the pre-resection line during the surgery were recorded.
Secondary Outcomes
- Postoperative complication rate(3 months)
- Operative outcomes(intraoperative)