Myopia control efficacy of Spectacle lenses with Highly aspherical lenslets (HAL) in high myopia.

This prospective controlled clinical trial will be conducted in Myopia Research Lab, L V Prasad Eye Institute, Hyderabad, and the study protocol will adhere to the tenets of Declaration of Helsinki. Participants will be recruited based on the inclusion and exclusion criteria either from The Infor Myopic Clinic, L V Prasad Eye Institute, Hyderabad or by advertisement in local media (newspaper), or approaching schools for referrals. An informed consent will be obtained from each participant (parent/guardian of participating child) after explaining the nature of the study. Assent will be obtained from the participating children. Detailed ocular and medical history will be elicited followed by comprehensive examination (visual acuity, slit lamp examination, open-field autorefraction, subjective refraction), pupillometry, specialty tests such as binocular vision assessments, axial length measurement, peripheral refraction, optical coherence tomography, corneal topography. All participants will undergo cycloplegic refraction after instillation of Tropicamide 1% eye drops. Measurements will be obtained thirty minutes after instillation of eye drops. Eligible participants will be called for the dispensing visit and then following study visits at 3 month, 6 months and 12 months. In each follow-up visits, the required ocular parameters such as visual acuity, slit lamp examination, axial length, peripheral refraction, open field autorefraction, subjective refraction, pupillometry, optical coherence tomography, corneal topography along with participant’s compliance to the spectacles provided will be assessed to analyze the efficacy of these spectacles in controlling myopia progression.