NCT01206153已完成4 期
Metformin for Treatment Antipsychotic Induced Amenorrhea in Female Schizophrenic Patients: a Double Blind, Placebo-controlled Study
Central South University1 个研究点 分布在 1 个国家目标入组 84 人开始时间: 2008年6月最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 84
- 试验地点
- 1
- 主要终点
- prolactin level
研究概览
简要总结
Antipsychotics such as risperidone could induce amenorrhea in schizophrenic patients. The investigators conducted a randomized, placebo-controlled study to test the efficacy of metformin for antipsychotic induced amenorrhea in schizophrenia patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •schizophrenia patient
- •amenorrhea for more than three months after antipsychotic treatment
排除标准
- •liver or renal diseases
- •pregnant or lactating women
- •cardiovascular diseases
- •hypertension or diabetes mellitus
研究组 & 干预措施
metformin
Experimental
干预措施: metformin (Drug)
结局指标
主要结局
prolactin level
the outcome measure assess a efficacy.
次要结局
- fasting glucose
研究者
研究点 (1)
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