Pre-operative 5% Dextrose Infusion & PONV
Not Applicable
Completed
- Conditions
- Nausea, Postoperative
- Registration Number
- NCT05947981
- Lead Sponsor
- Cairo University
- Brief Summary
With this study, we aim to compare the efficacy of pre-operative dextrose-containing fluid infusion with other fluid for the prevention of PONV in middle ear surgeries.
- Detailed Description
We hypothesized that maintenance of stable level of blood glucose in addition to adequate hydration through preoperative intravenous dextrose 5% infusion will have a rule in decreasing the incidence and severity of PONV; as it reduces insulin resistance and decreases gastric acid secretion; which may contribute to PONV.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 105
Inclusion Criteria
- ASA physical status I and ll.
- Patients undergoing middle ear surgeries, mastoidectomy, or tympanoplasty
Exclusion Criteria
- history of dependence or use of antiemetics
- history of motion sickness
- presence of psychiatric illness
- pregnant and lactating women
- cardiovascular disorders (Ischemic heart diseases, congestive heart failure and valvular diseases)
- Diabetic patients
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method PONV 24 hours incidence
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Faculty of Medicine- Cairo University
🇪🇬Cairo, Egypt
Faculty of Medicine- Cairo University🇪🇬Cairo, Egypt