Effect of Ushiradya Taila Matra Basti and Kanchanar Guggulu in the management of Mootraghata w.s.r to Benign Prostatic Hyperplasia

Phase 1/2

Recruiting

• Conditions: Age 40 years to 70years.Patients having classical signs and symptoms of Mootraghata / BPH

• Registration Number: CTRI/2017/04/008306
• Lead Sponsor: IPGT and RA GAU Jammagar GUJARAT

Brief Summary

In clinical study, patients were selected and divided randomly into two groups and treated with the trial formulations of *kanchanar guggulu* in group-A and *Ushiradya* *Taila* *Matra Basti* alongwith *Kanchanar Guggulu* in group-B. The treatment was instituted for the duration of 21 days. Out of 35 patients, 17 patients in both groups were completed the therapy as well as follow up period & 1 patient from  group A was drop out due to diagnosis of carcinoma of prostate. All the patients were assessed as per subjective and objective gradation during the study & the findings were recorded in the research proforma. The entire study and its data related to effect of therapy were plotted after statistical calculations on all over the subjective & objective parameters.

Ø  Maximum improvement was seen in 1 patient (5.88%) and 2 patients (11.76%) in group A and B respectively.

Ø  Moderate improvement was seen in 6 patients (35.29%) and 8 patients (47.06%) in group A and B respectively.

Ø  Mild improvement was observed in 9 patients (52.95%) and  7 patients (41.18%) in group A and B respectively.

Ø  At the end of therapy, none of patient had got complete cure and 1 patient was seen unchanged (5.88%) result in group A.

Ø  Overall group B (47.99 %) has shown better result than group A (39.62 %) in all parameters.

In subjective parameters(IPSS), group B had shown better result i.e. 83.69% than the group A (74.75%). But, when data was analyzed statistically with Wilcoxon Rank Sum Test (Mann Whitney), non significant difference between these groups was recorded.

In all objective parameters group-B had shown better effect i.e. 50.44% than group-A (41.82%). But, when data was analyzed statistically with Unpaired ‘t’ test, insignificant difference between these groups was recorded.

Finally study can be concluded that *Kanchanar Guggulu* orally and*Ushiradya Taila Matra Basti* is safe easy to apply and effective in symptomatic management of *Mootraghata* (BPH) without any side effect.

Detailed Description

Not available

Study Timeline

• Study Start: 2017-02-14
• Last Update Posted: 2018-06-27

Recruitment & Eligibility

• Status: Open to Recruitment
• Sex: Male
• Target Recruitment: 30

Inclusion Criteria

• Age 40 years to 70 years.
• Patients having classical signs and symptoms of Mootraghata / BPH.

Exclusion Criteria

• Age below 40 years and above 70 years.
• Patients of malignancy, congenital deformities of urogenital tract or any abdomino- pelvic pathology other than BPH.
• Systemic diseases like Uncontrolled Hypertension and diabetes mellitus, Tuberculosis , Paralysis, Parkinsonism etc.
• will be excluded.
• Known case of cardiac diseases.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
this work will useful in symptomatic treatment of BPH without surgery Progress in the signs and symptoms	21 days
based on the standard pattern will be applied	21 days
before and after treatment	21 days

Secondary Outcome Measures

Name	Time	Method
this work will helps patients of BPH and give them symptomatic relief	Progress in the signs and symptoms

Trial Locations

Locations (1)

IPGT RA GAU Jamnagar; 🇮🇳 Jamnagar, GUJARAT, India

IPGT RA GAU Jamnagar

🇮🇳Jamnagar, GUJARAT, India

Dr Bhagirath Sankaliya

Principal investigator

7698570056

drbhagirath15@gmail.com