Comparison of Ocular biometric Parameters in Patients diagnosed with Nanophthalmos and in patients with Primary Angle Closure Disease
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- To analyze the ocular biometric parameters in patients with Nanophthalmos and in patients with Primary Angle Closure disease
研究概览
简要总结
| Nanophthalmos is a condition |
| characterized by reduced size of the anterior and posterior segments of the |
| eye with abnormally thickened sclera |
Diagnostically, axial length (AL) below 20.5 mm and Retinochoroidal scleral thickness (RCS) > 1.7 mm with no associated ocular malformations are grouped under this special subtype of microphthalmos. The characteristic features include abnormally thickened sclera, short AL, small corneal diameter, and crowding of the anterior chamber secondary to a high lens to eye volume ratio. The pathophysiological mechanisms in these two conditions are similar, however, the role of thickened sclera in influencing the angle closure in nanophthalmos is unexplored. Also, this study will help in understanding the secondary angle closure component in short eyes.
Anterior segment optical coherence tomography (AS-OCT), Ultrasound biomicroscopy (UBM), A scan and B-mode USG can help assess the anterior and posterior segment biometric parameters in these eyes.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 40.00 Year(s) 至 80.00 Year(s)（—）
- 性别
- All
入选标准
- •Diagnosed with nanophthalmos.
- •study group Diagnosed with primary angle closure disease -control group.
排除标准
- •Patients with corneal opacities 2) Patients who have undergone YAG peripheral iridotomy or cataract surgery.
结局指标
主要结局
To analyze the ocular biometric parameters in patients with Nanophthalmos and in patients with Primary Angle Closure disease
时间窗: 6 months
次要结局
- It may further support the continuation of understanding the risk factors with a large population
研究者
Dr Sharmila Rajendrababu
Aravind Eye Hospital and Postgraduate Institute of Ophthalmology