HILO-HF Registry: High Versus Low SpO2 Oxygen Therapy in Patients With Acute Heart Failure
Completed
- Conditions
- Acute Heart Failure
- Registration Number
- NCT03110042
- Lead Sponsor
- University of Alberta
- Brief Summary
The HILO-HF Registry is a single centre registry that will be performed to provide information on the usual baseline oxygen saturation (SpO2) in patients presenting to ED with a primary ED diagnosis of AHF
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
- Patients >40 years of age presenting to the ED with AHF
- With or without tested BNP
- With or without admission to hospital for treatment of HF\
- Patients must be recruited within the first 24 hours of presenting to the ED.
Read More
Exclusion Criteria
- Patients on home oxygen
- Patients with known prior hypercapnic failure (PaCO2>50 mmHg)
- Asthma
- Primary pulmonary hypertension
- Patients requiring urgent positive pressure ventilation or intubation or on >10 L/min oxygen
Read More
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change in blood oxygen saturation levels from baseline to 72 hours 72 hours
- Secondary Outcome Measures
Name Time Method 30-day composite clinical event (all-cause mortality, HF readmission, days alive and out of hospital) 30days Dyspnea on visual analogue scale (VAS) to 72 hours 72 hours Change in global symptoms using Patient Global Assessment (PGA) measure to 72 hours 72 hours Rate of patients with Worsening Heart Failure 7 days Change in Peak Expiratory Flow 72 hours
Trial Locations
- Locations (1)
University of Alberta Hospital / Mazankowski Alberta Heart Institute
🇨🇦Edmonton, Alberta, Canada