The Research based on MRI to investigate the role of tVNS in regulate inflammation and reward loops in Recurrent MDD Patients
Phase 1
- Conditions
- major depressive disorder
- Registration Number
- ITMCTR1900002288
- Lead Sponsor
- Beijing Hospital of Traditional Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
(1) ICD-10 diagnosis standard of a depressive episode;
(2) Aged 18 and 60 years;
(3) Hamilton Anxiety ScaleHAMA=7 Meets;
(4) Junior high or higher level education;
(5) Right-handed;
(6) Signing informed consent.
Exclusion Criteria
(1) Ongoing addiction to drugs and alcohol;
(2) Organic mental disorder;
(3) Drug-induced depression;
(4) Pregnant women;
(5) Postpartum depression.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Inflammatory marker;Hormone level;resting-state functional magnetic resonance imaging;
- Secondary Outcome Measures
Name Time Method