Comparison of Efficacy of Microneedling With Platelet Rich Plasma Vs Microneedling With Topical Insulin in the Treatment of Acne Scars

Not Applicable

Recruiting

• Conditions: Post-acne Atrophic Scars

• Registration Number: NCT06978361
• Lead Sponsor: Khyber Teaching Hospital

Brief Summary

This study compares the outcome of two procedures for the treatment of atrophic acne scars.

Detailed Description

Post acne scars develop due to severely inflamed and nodulocystic acne. Numerous methods exist for the treatment of post acne scars including lasers , microneedling and chemical peels etc . This study is to compare the efficacy two procedures.

Study Timeline

• Status Verified: 2025-02
• Study Start: 2025-03-01
• Study First Submitted: 2025-05-10
• Study First Submitted QC: 2025-05-16
• Last Update Submitted: 2025-05-16
• Study First Posted: 2025-05-18
• Last Update Posted: 2025-05-18
• Primary Completion: 2025-12-31
• Study Completion: 2025-12-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 116

Inclusion Criteria

Patients confirmed with post-acne atrophic scars . No prior treatment for scars in last 6 months.

Exclusion Criteria

• Patient with active acne or other skin conditions (e.g eczema , psoriasis). Patients on oral or topical retinoids. Pregnant or lactating Mothers. Patients with recurrent herpes simplex infection. Previous Hx of keloids / hypertrophic scarring. Deranged blood glucose levels. Bleeding disorders

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Efficacy of treatment	6 months	Efficacy will be determined by using the Goodman and Baron's Scarring Grading System as" Percentage of decrease in acne scar grade" i.e calculated through subtracting post treatment grade from pre treatment grade and then multiplying it with 100 in both treatment groups .

Trial Locations

Locations (1)

Khyber Teaching Hospital; 🇵🇰 Peshawar, KPK ,Pakistan, Pakistan