Effects of Different Ventilatory Strategy During Bronchoscopy

The First Affiliated Hospital of Guangzhou Medical University0 sites150 target enrollmentJuly 20, 2023

ConditionsBronchoscopy

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Bronchoscopy
Sponsor: The First Affiliated Hospital of Guangzhou Medical University
Enrollment: 150
Primary Endpoint: Compare the intraoperative oxygenation.
Status: Not yet recruiting
Last Updated: 2 years ago

Overview Investigators Eligibility Criteria Outcomes Similar Trials

Overview

Brief Summary

The execution of diagnostic-therapeutic investigations by bronchial endoscopy can expose the patient to hypoxemia. For this reason, oxygen therapy is administered at low or high flows during the course of bronchoscopic procedures.

Our study aim was to evaluate the efficacy and complications of High-flow nasal oxygen (HFNO) via Supraglottic jet oxygenation and ventilation (SJOV)during flexible bronchoscopy.

Registry

clinicaltrials.gov

Start Date

July 20, 2023

End Date

June 30, 2025

Last Updated

2 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

The First Affiliated Hospital of Guangzhou Medical University

Responsible Party

Principal Investigator

Liya Lu

associate chief physician

The First Affiliated Hospital of Guangzhou Medical University

Eligibility Criteria

Inclusion Criteria

•need for bronchial endoscopy

Exclusion Criteria

•life-threatening cardiac aritmia or acute miocardical infarction within 6 weeks need for invasive or non invasive ventilation presence of pneumothorax or pulmonary enphisema or bullae recent (within 1 week) thoracic surgery presence of chest burns presence of tracheostomy pregnancy nasal or nasopharyngeal diseases dementia lack of consent or its withdrawal

Outcomes

Primary Outcomes

Compare the intraoperative oxygenation.

Time Frame: During bronchoscopy, an average of 0.5 hour.

The study will monitor the SpO2， heart rate(HR) and mean arterial pressure (MAP) during the procedure.

Secondary Outcomes

Arterial blood gases(At end of of bronchoscopy,an average of 0.5 hour after bronchoscope insertion.)
Assess the regional ventilation distribution by Electrical impedance tomography .(During bronchoscopy, an average of 0.5 hour.)