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Improving the School Vaccination Experience: What CARDs Are You Going to Play?

Not Applicable
Terminated
Conditions
Vaccine Adverse Reaction
Fear
Vaccination; Complications
Interventions
Other: Multi-faceted knowledge translation intervention
Registration Number
NCT03966300
Lead Sponsor
University of Toronto
Brief Summary

Vaccination hesitancy is identified as a threat to global health by the World Health Organization (WHO). For adolescents undergoing vaccination at school, prior studies demonstrate that concerns about pain and/or fear of needles contribute to negative experiences with vaccination and non-compliance with vaccination. The investigators developed an intervention that addresses vaccination hesitancy. In this study, investigators will evaluate the effectiveness of this intervention in a randomized controlled trial.

Detailed Description

Vaccination hesitancy is identified by the World Health Organization (WHO) as one of ten threats to global health. The WHO's 3C model of vaccination hesitancy identifies 3 domains of vaccine hesitancy: 1) Confidence (trust in health care providers), 2) Complacency (perceived importance of vaccine-preventable disease) and 3) Convenience (improving clinic processes). The investigators developed a multifaceted knowledge translation intervention that addresses vaccination hesitancy in school-based vaccinations. The intervention is called The CARD(TM) System (C-Comfort, A-Ask, R-Relax, D-Distract). CARD is a framework for delivering vaccinations that is student-centred and promotes coping. CARD integrates evidence-based interventions related to planning and execution of school vaccination clinics to directly tackle all 3 domains of vaccination hesitancy. It tackles Confidence by improving pain/fear management (it teaches students and public health staff how to reduce student symptoms which improves the vaccination experience and improves student trust in health care providers). It tackles Complacency by educating students about what vaccines are, why they are needed, community immunity, as well as the specific diseases they are being protected against. It tackles Convenience by improving school-based clinic processes by integrating student preferences (e.g., privacy, having a support person present).

In this randomized controlled trial, the investigators will evaluate the impact of CARD (vs. usual care) on student important outcomes and process outcomes.

Recruitment & Eligibility

Status
TERMINATED
Sex
All
Target Recruitment
1919
Inclusion Criteria
  • grade 7 students eligible for vaccination at school
  • public health staff working in the school vaccination program
Exclusion Criteria
  • unable to understand and read English

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
CARD (multi-faceted knowledge translation intervention)Multi-faceted knowledge translation interventionCARD will be integrated into the school vaccination program. This includes pre-vaccination day preparation (e.g., planning of clinic spaces, student and school staff education about CARD) and vaccination day activities (e.g., clinic set-up, processes for triaging students, implementing pain/fear/fainting mitigation interventions from CARD during vaccination)
Primary Outcome Measures
NameTimeMethod
Student fearwithin 5 minutes after vaccination

student self-reported fear during vaccination, rated on a 0-10 scale

Secondary Outcome Measures
NameTimeMethod
Student dizzinesswithin 5 minutes of vaccination

student self-reported dizziness during vaccination, rated on a 0-10 scale

Willingness to be vaccinatedwithin 5 minutes after vaccination

student self-reported willingness to be vaccinated, as assessed using a 5-point likert scale (higher number represents better outcome)

Utilization of coping strategieswithin 5 minutes after vaccination

use of individual coping strategies during vaccination (distraction, topical anesthetic, privacy, support person, deep breathing, muscle tension), yes/no, as assessed by immunizer using Documentation Checklist

Uptake of vaccinationby end of school year

proportion of students vaccinated (overall and for each vaccine)

Implementation success of CARDwithin 3 months of vaccination clinics

perceptions of implementation success of CARD program delivery as reported by CARD implementers (primary targets) using the CARD Global Impression Checklist, individual questions (5-point likert scale, higher number represents better outcome). This information will be supplemented with information from focus groups with implementers and study notes

Knowledge of effective coping strategieswithin 3 months after vaccination clinics

knowledge of effective coping strategies, as assessed using a 10-point investigator-developed knowledge test, administered to implementers

Satisfaction with CARDwithin 5 minutes after vaccination

student self-reported satisfaction with CARD, as assessed using Student Feedback Survey, individual questions (5-point likert scale, higher number indicates better outcome)

Student painwithin 5 minutes after vaccination

student self-reported pain during vaccination, rated on a 0-10 scale

Student faintingwithin 1 hour after vaccination

student fainting during vaccination, yes/no, as assessed by immunizer

Student post-immunization stress-related responseswithin 1 hour after vaccination

student post-immunization stress-related responses, yes/no, as assessed by immunizer using the WHO immunization Stress Responses Criteria

Compliance with CARDwithin 3 months of vaccination clinics

percent compliance with CARD implementation as assessed by implementers using a CARD compliance checklist. This information will be supplemented with information from focus groups with implementers and study notes

Perceptions about pain and fearwithin 3 months of vaccination clinics

perceptions about pain and fear, as assessed using a 5-point likert scale (higher number represents better outcome) for implementers

Perceptions about vaccination programwithin 3 months of vaccination clinics

perceptions about vaccination program, as assessed using the Vaccination Program Global Impresssion Checklist, individual questions (5-point likert scale, higher number represents better outcome) for implementers

Trial Locations

Locations (1)

Wellington Dufferin Guelph Public Health

🇨🇦

Guelph, Ontario, Canada

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