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Clinical Trials/NCT03966300
NCT03966300
Terminated
Not Applicable

Playing CARDs to Improve the Vaccination Experience at School: a Cluster Randomized Controlled Trial

University of Toronto1 site in 1 country1,919 target enrollmentSeptember 19, 2019

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Vaccine Adverse Reaction
Sponsor
University of Toronto
Enrollment
1919
Locations
1
Primary Endpoint
Student fear
Status
Terminated
Last Updated
4 years ago

Overview

Brief Summary

Vaccination hesitancy is identified as a threat to global health by the World Health Organization (WHO). For adolescents undergoing vaccination at school, prior studies demonstrate that concerns about pain and/or fear of needles contribute to negative experiences with vaccination and non-compliance with vaccination. The investigators developed an intervention that addresses vaccination hesitancy. In this study, investigators will evaluate the effectiveness of this intervention in a randomized controlled trial.

Detailed Description

Vaccination hesitancy is identified by the World Health Organization (WHO) as one of ten threats to global health. The WHO's 3C model of vaccination hesitancy identifies 3 domains of vaccine hesitancy: 1) Confidence (trust in health care providers), 2) Complacency (perceived importance of vaccine-preventable disease) and 3) Convenience (improving clinic processes). The investigators developed a multifaceted knowledge translation intervention that addresses vaccination hesitancy in school-based vaccinations. The intervention is called The CARD(TM) System (C-Comfort, A-Ask, R-Relax, D-Distract). CARD is a framework for delivering vaccinations that is student-centred and promotes coping. CARD integrates evidence-based interventions related to planning and execution of school vaccination clinics to directly tackle all 3 domains of vaccination hesitancy. It tackles Confidence by improving pain/fear management (it teaches students and public health staff how to reduce student symptoms which improves the vaccination experience and improves student trust in health care providers). It tackles Complacency by educating students about what vaccines are, why they are needed, community immunity, as well as the specific diseases they are being protected against. It tackles Convenience by improving school-based clinic processes by integrating student preferences (e.g., privacy, having a support person present). In this randomized controlled trial, the investigators will evaluate the impact of CARD (vs. usual care) on student important outcomes and process outcomes.

Registry
clinicaltrials.gov
Start Date
September 19, 2019
End Date
November 22, 2019
Last Updated
4 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Anna Taddio

Professor

University of Toronto

Eligibility Criteria

Inclusion Criteria

  • grade 7 students eligible for vaccination at school
  • public health staff working in the school vaccination program

Exclusion Criteria

  • unable to understand and read English

Outcomes

Primary Outcomes

Student fear

Time Frame: within 5 minutes after vaccination

student self-reported fear during vaccination, rated on a 0-10 scale

Secondary Outcomes

  • Student dizziness(within 5 minutes of vaccination)
  • Willingness to be vaccinated(within 5 minutes after vaccination)
  • Utilization of coping strategies(within 5 minutes after vaccination)
  • Uptake of vaccination(by end of school year)
  • Implementation success of CARD(within 3 months of vaccination clinics)
  • Knowledge of effective coping strategies(within 3 months after vaccination clinics)
  • Satisfaction with CARD(within 5 minutes after vaccination)
  • Student post-immunization stress-related responses(within 1 hour after vaccination)
  • Student pain(within 5 minutes after vaccination)
  • Student fainting(within 1 hour after vaccination)
  • Compliance with CARD(within 3 months of vaccination clinics)
  • Perceptions about pain and fear(within 3 months of vaccination clinics)
  • Perceptions about vaccination program(within 3 months of vaccination clinics)

Study Sites (1)

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