JPRN-UMIN000043657已完成未知
Effect of sacubitril/valsartan versus valsartan on blood pressure in hypertensive patients with chronic heart failure and chronic kidney disease, a parallel-group randomized controlled trial - SaVa-CKD trial
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 入组人数
- 62
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 20years-old 至 ot applicable（—）
- 性别
- All
入选标准
- 未提供
排除标准
- •1.Bilateral renal artery stenosis or renal artery stenosis in piece renal patients 2.Pregnancy, lactating women 3.Serum potassium >5.5mEq/L 4.Ischaemic heart disease and stroke in 6 months prior to Screening 5.History if angioedema 6.Severe liver failure(Child-Pugh C) or ALT/AST is more than twice the normal upper limit at Screening 7.History of hypersensitivity to sacubitril/valsartan 8.Diabetes mellitus on current treatment with aliskiren 9.Patients judged by the investigator to be unsuitable as subjects 10.Chronic lung disease requiring home oxygen administration 11.Patients who need to introduce renal replacement therapy within 6 months 12.Clinic or home systolic blood pressure is 200mmHg or higher. 13.Heart failure requiring oxygen administration 14.Serum Cr level increased by more than 30% in the last 3 months 15.If patients take ARB at registration, the dose is higher than half of the maximum daily dose
研究者
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