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A phase I randomized crossover trial study of effect of Flow practice to brain and body cellular health

Phase 1
Conditions
Flow practice
Mindfulness
sleep
Health volunteer 25&#45
BDNF
healthcare worker
55 years oldMale and female nurse working in Chiang Mai university hospital.
Mitochondria function
cognitive
Registration Number
TCTR20180313001
Lead Sponsor
Chiang Mai university
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending (Not yet recruiting)
Sex
All
Target Recruitment
50
Inclusion Criteria

1.age 25-60 year-old
2.Positive for impaired well being screened by 5 items self satisfaction score (Diener et al)

Exclusion Criteria

1.active seriously illness ie. active cancer, symptomatic organ failure, HIV and severe psychological illness. (
2. Unable to attend the complete two 3days-retreat residential program.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
mitochnodrial function a day before and after intervention oxidative stress (8OH2dG),Neuroplasticity marker a day before and after intervention Serum BDNF level ,heart rate variability (HRV) a day before and after intervention EKG low frequency to high fre,central blood presssure a day before and after intervention SphygmoCor,Insulin resistance a day before and after intervention insulin level
Secondary Outcome Measures
NameTimeMethod
cognitive function baseline and 3 months after intervention Montreal cognitive assesment (MOCA),Sleep quality baseline and 3 months after intervention Pitt's burg sleep questionaire
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