Comparison of Conventional Dialysis and the Allient System
Not Applicable
- Conditions
- End Stage Renal DiseaseChronic Kidney Failure
- Registration Number
- NCT00788905
- Lead Sponsor
- Renal Research Institute
- Brief Summary
The purpose of the study to determine whether the level of inflammation may be decreased, the lifespan of red blood cells increased and the clearance of waste products in the blood improved through the use of the Allient System as compared to conventional hemodialysis.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
- Maintenance in-center hemodialysis
- Age greater than or equal to 18 years
- Has been on hemodialysis for at least 4 months
- Uses a standard single-pass dialysis machine with a high-flux dialyzer
Exclusion Criteria
- Hospitalization during the 8 weeks preceding enrollment
- Infection requiring antibiotic treatment during the 8 weeks preceding enrollment
- Central venous cather as dialysis access
- Uncontrollable blood coagulation anomalies
- Smokers
- Dialysis regimen other than 3 times weekly
- In ability to understand the English language and give informed consent for participation in the study
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Primary Outcome Measures
Name Time Method Clearance of specific waste products from blood determined through subject blood and dialysate samples 3 weeks
- Secondary Outcome Measures
Name Time Method Inflammation as determined by levels of specific inflammatory markers 3 weeks Red blood cell lifespan determined through a measurement of CO in the subject's breath 3 weeks
Trial Locations
- Locations (3)
Irving Place Dialysis Center
🇺🇸New York, New York, United States
Upper Manhattan Dialysis Center
🇺🇸New York, New York, United States
Yorkville Dialysis Center
🇺🇸New York, New York, United States
Irving Place Dialysis Center🇺🇸New York, New York, United States