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Effect of Allopurinol in lowering blood pressure in hemodialysis patients

Not Applicable
Conditions
Condition 1: Hypertension. Condition 2: Hyperuricemia.
Hypertensive renal disease, Hypertensive heart and renal disease , Secondary hypertension
Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease Asymptomatic hyperuricaemia
I12, I13,
Registration Number
IRCT138902043325N2
Lead Sponsor
Zanjan University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
55
Inclusion Criteria

having high level of serum uric acid (serum uric acid level greater than 6.5 mg/dl (men) or greater than 5.5 mg/dl (women). This definition was based on analyses from the Atherosclerosis Risk in Communities (ARIC) Study;
Exclusion criteria: uric acid level of serum less than 6.5 for men and less than 5.5 for women, known history of allopurinol hypersensitivity or those who already were on allopurinol

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Blood pressure. Timepoint: Baseline, at the beginning of each phase, each week for 3 month during each phase. Method of measurement: sphygmomanometer.
Secondary Outcome Measures
NameTimeMethod
Blood level of uric acid. Timepoint: at the begining of study and after 3 months. Method of measurement: laboratory techniques.
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