Effect of Allopurinol in lowering blood pressure in hemodialysis patients
Not Applicable
- Conditions
- Condition 1: Hypertension. Condition 2: Hyperuricemia.Hypertensive renal disease, Hypertensive heart and renal disease , Secondary hypertensionHyperuricaemia without signs of inflammatory arthritis and tophaceous disease Asymptomatic hyperuricaemiaI12, I13,
- Registration Number
- IRCT138902043325N2
- Lead Sponsor
- Zanjan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 55
Inclusion Criteria
having high level of serum uric acid (serum uric acid level greater than 6.5 mg/dl (men) or greater than 5.5 mg/dl (women). This definition was based on analyses from the Atherosclerosis Risk in Communities (ARIC) Study;
Exclusion criteria: uric acid level of serum less than 6.5 for men and less than 5.5 for women, known history of allopurinol hypersensitivity or those who already were on allopurinol
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Blood pressure. Timepoint: Baseline, at the beginning of each phase, each week for 3 month during each phase. Method of measurement: sphygmomanometer.
- Secondary Outcome Measures
Name Time Method Blood level of uric acid. Timepoint: at the begining of study and after 3 months. Method of measurement: laboratory techniques.