Double Regional Anesthesia in Video Assisted Thoracoscopy
Phase 4
Completed
- Conditions
- Video Assisted ThoracoscopyAnesthesia
- Interventions
- Drug: Serratus plane block and paravertebral blockDrug: paravertebral block
- Registration Number
- NCT03852862
- Lead Sponsor
- University Hospital, Rouen
- Brief Summary
Monocentric, randomized, controlled, single-blind study who's aim is to demonstrate the efficacy of the association of paravertebral block and serratus plane block with paravertebral block alone
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 112
Inclusion Criteria
- Patient aged 18 to 75 years;
- Programmed for unilateral videothoracoscopy for anatomical resection (segmentectomy, lobectomy);
- Subject affiliated to a social security scheme;
- Subject having signed an informed consent
Exclusion Criteria
- Chronic treatment with opiates;
- Contraindication to administration of morphine;
- Allergy to local anesthetics or contraindications to the use of ropivacaine;
- Contraindication to the realization of paravertebral blocks and serratus;
- Pregnancy, breastfeeding;
- Severe obesity (BMI > 40 kg/m²);
- Renal impairment (GFR < 30 mL/min) or known severe hepatic impairment;
- Difficulties of comprehension preventing the collection of consent and the realization of the study;
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Serratus plane block with paravertebral block Serratus plane block and paravertebral block Association of Serratus plane block and paravertebral block for anesthesia paravertebral block alone paravertebral block Paravertebral block for anesthesia
- Primary Outcome Measures
Name Time Method Number of opioids drug administrated 24 hours postoperatively
- Secondary Outcome Measures
Name Time Method Length of stay in recovery room 24 hours postoperatively Total duration of hospitalization during the 28 days postoperatively
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie the analgesic synergy of paravertebral and serratus plane blocks in VATS?
How does the combination of paravertebral and serratus plane blocks compare to standard thoracic epidural analgesia in VATS outcomes?
Are there specific biomarkers that predict enhanced postoperative pain control with dual regional anesthesia in thoracic surgery?
What are the potential adverse event profiles of serratus plane block when combined with paravertebral block in VATS?
What alternative anesthetic combinations or adjuvants are being explored for VATS in phase 4 trials like NCT03852862?
Trial Locations
- Locations (1)
Rouen University Hospital
🇫🇷Rouen, France
Rouen University Hospital🇫🇷Rouen, France