Ayurvedic Management of Dyslipidemia Through Virechan Karma And Shaman Snehpana
- Conditions
- Hyperlipidemia, unspecified. Ayurveda Condition: MEDOROGAH,
- Registration Number
- CTRI/2025/04/084599
- Lead Sponsor
- Government Akhand Anand Ayurved College
- Brief Summary
**Research question**
Whether Shaman Snehpana and Virechana Karma are equally effective or not in the management of Dyslipidemia?
**Hypothesis**
**NULL HYPOTHESIS [HO]**There is no significant difference in the effect between Shamana Snehapana and Virechan karma in the Management of dyslipidemia
**Alternative Hypothesis**
**(H1)** Shamana Snehapana is more effective than Virechana Karma in the management of dyslipidemia
**(H2)** Virechana Karma is more effective than Shamana Snehapana in the management of dyslipidemia
**AIM:**
To evaluate and compare the efficacy of Shamana Snehapana and Virechana Karma in the management of Dyslipidemia
**OBJECTIVES**
To study the complete etiopathology, symptomatology and progress of Dyslipidemia According to Ayurveda as well as modern science
To study the efficacy of Shamana Snehapana in the management of dyslipidemia
To study the efficacy of Virechan in the management of dyslipidemia
To study Virechan karma according to all Ayurvedic texts
**OBJECTIVE CRITERIA**
LIPID PROFILE
TOTAL CHOLESTEROL more than 200 mgdL
LDL more than100 mgdl
TRIGLYCERIDES more than150 mgdL
HDL less than 40 mgdL
APOLIPOPROTEIN B more than 120mgdL
**SUBJECTIVE CRITERIA**
There are no signs and symptoms of dyslipidemia
**Inclusion criteria**
1Age between 18 to 60 yrs
2 On the basis of National Cholesterol Education Program (NCEP) Adult Treatment Plan(ATP) III
Guidelines patients having
TOTAL CHOLESTEROL more than 200 mgdL
OR
LDL more than 100 mgdL
OR
TRIGLYCERIDES more than 150 mgDl
OR
HDL less than 40 mgDl
OR
APOLIPOPROTEIN B more than 120mgdL
Patients who are Snehapana Yogya
Patients who are Virechana Yogya
**Exclusion criteria**
Age below 18 years and more than 60 years
Patients with uncontrolled HTN uncontrolled DM
Pregnant / lactating women
Virechan Ayogya
Snehpana Ayogya
Heart Diseases, Kidney Diseases Stroke Liver Disease
Pulmonary Dysfunction or COPD
Patients with a history of any acute or chronic infectious diseases like TB AIDS and Other STDs
Patients taking medications like corticosteroids hormonal therapy
antidepressants or any other drugs which may affect the outcome of the
study
**Investigations**
Following investigations will be carried out before and after treatment
LIPID PROFILE
APOLIPOPROTEIN B
To rule out other pathologies CBC and Urine (R and M) will be done
**Study Design**
**Study type**: Intervention
**Purpose**: Treatment
**Masking**: Open labelled. no masking
**Study design:** Randomized clinical trial
**Allocation:**Computer generated randomization
**Timing:** Prospective
**End point**: Efficacy and safety
**No.** of Groups: 2
**Sample size:** 30 patients (15 patients in each group)
**Details of interventions**
**GROUPING**: Selected patients will be divided randomly into two group
**GROUP A**
15 patients will be treated with Shamana Snehapana
**GROUP B**
15 patients will be treated with Virechana Karma
**GROUP A: SHAMAN SNEHAPANA WITH TRIPHALADI TAIL**
| | | | |
| --- | --- | --- | --- |
|DRUGDOSE & ANUPANA ADMINISTRATION
TIME
DURATION
|Triphala
Trikatu and
Saindhava
Siddha Taila
30-50ml
With Mudga Yusha
Annakala Prakankshit28 Days
**GROUP B: VIRECHANA KARMA**
Procedure is divided into 3 parts as follows
**PURVAKARMA**
| | | |
| --- | --- | --- |
|**PROCEDURE****DRUG AND DOSE****DURATION**
| Deepana and Pachana Drug Trikatu Churna
Dose 4 to 6 gm per day (2
to 3gm twice a day per Aatura
Agni)
Time of
Administration Before
Food
Anupana Ushna Jala
Route Oral Route
3 to 5 Days (Till the
Karma appearance of
Samyak Deepana
and Pachana
Lakshana observed)
| Snehapana Drug Tila taila 3 to 7 Days
Dose 20 to 40 ml starting dose in vardhamana Krama
(as per Aatura-Kostha and Agni)
Time of Administration
EarlyMorning at empty
stomach
Anupana Ushna Jala
Route Oral Route
Diet Light Diet (drava ushna
annabhishyan natisnidgha asankirn
a)
3 to 7 Days
| Sarvanga Abhyanga and baspa sweden
Drug Tila taila QS
(Approx 50 ml)
For 1st 2nd 3rd day during
vishrama kala after
completionof abhyantar
snehapana and also 4th day
prior to Virechan karma
4days
**PRADHAN KARMA**
| | | |
| --- | --- | --- |
|**PROCEDURE****DRUG AND DOSE****DURATION**
|Virechan karmaDrug Abhyadimodak 8-10 Tab Anupana Sheet Jala Time of Administration Sheleshma Kale Gate after 10am1 DAY
**PASCHAT KARMA**
| | | |
| --- | --- | --- |
|**PROCEDURE****DRUG AND DOSE****DURATION**
|Samsarjana
Krama
Diet Plan will be fixed as per
shuddhi for 3 to 7 days
The regimen of 7 5 3 days
will be fixed according to the Pravar Madhyama Avara Shuddhi
The sequence of Peya Vilepi
AkritMudga Yusha andOdana
Krita Mudga Yusha andOdana
will be
served for 3 2 1 aaharakala
According to the type of
shuddhi
3 to 7 Days
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- All
- Target Recruitment
- 30
1 Age between 18 to 6O years 2 Patients having Total Cholestrol more than 2OOmgdl OR LDL more than 1OO mgdl OR Triglycerides more than 15O mgdl OR HDL less than 4O mgdl OR Apolipoprotein B more than 12O mgdl 3 Snehpana yogya 4 Virechan yogya.
1 Age below 18 and more than 6O years 2 Patients with uncontrolled HTN and DM 3 Pregnant and lactating women 4 Virechan Ayogya 5 Snehpana Agyogya 6 Known case of heart disease Stroke liver disease COPD 7 Acute or chronic infectious diseases like TB STDs AIDS 8 On medications like corticosteroids, hormonal therapy antidepressants.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Outcome will be based on LIPID PROFILE OR Apolipoprotein B before and after treatment that is will be based on objective criterion 1 month Patients having 1 month LDL more than 1OO mgdl OR 1 month HDL less than 4O mgdl OR 1 month Apolipoprotein B more than 12O mgdl 1 month Total Cholestrol 1 month LDL 1 month Triglycerides 1 month HDL 1 month Apolipoprotein B 1 month Total Cholestrol more than 1 month 2OOmgdl OR 1 month Triglycerides more than 15O 1 month mgdl OR 1 month
- Secondary Outcome Measures
Name Time Method Patients will be assessed by blood investigations cbc, urine routine and microscopic. 1 month
Trial Locations
- Locations (1)
Government Akhandanand Ayurved College
🇮🇳Ahmadabad, GUJARAT, India
Government Akhandanand Ayurved College🇮🇳Ahmadabad, GUJARAT, IndiaDr Swetlana UpretiPrincipal investigator8979269473swatiupreti7@gmail.com