The international Mind, Activities and urban Places study (iMAP study): Building the evidence base on the relationships between environment, active living and cognitive health

Not Applicable

Recruiting

• Conditions: Cognitive function; Brain health; Health behaviors; Environmental risk factors; Mental Health - Studies of normal psychology, cognitive function and behaviour; Public Health - Epidemiology

• Registration Number: ACTRN12619000817145
• Lead Sponsor: Australian Catholic University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-06-04
• Last Update Posted: 16 February 2021

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 1800

Inclusion Criteria

50-79 year old community dwellers who are able to walk outside their home for at least 5 minutes without major difficulties, who are able to speak and write in English and without major diagnosed mental or physical health conditions.

Exclusion Criteria

All conditions need to be diagnosed by an appropriate health professional (e.g., general practitioner, neurologist, psychiatrist).

1. Cancer within the past 5 years (exceptions: surgically removed skin cancers and untreated prostate cancer)
2. Cerebral palsy
3. Colour blindness
4. Dementia
o Alzheimer’s disease (AD)
o Frontotemporal dementia (FTD)
o Lewy body disease
o Normal pressure Hydrocephalus
o Vascular dementia
o Any other dementia
5. Heart attack – if experienced significant loss of conscientiousness that resulted in brain injury or impairment
6. Medical conditions
o Lung disease (chronic & severe)
o Kidney disease (chronic & severe)
o Thyroid - hypothyroidism (e.g., Hashimoto’s disease) or hyperthyroidism (e.g., Graves disease)
7. Moderate or severe head injury (e.g., traumatic brain injury (TBI), acquired brain injury (ABI))
8. Mild cognitive impairment (MCI)
9. Neurological conditions
o Epilepsy
o History of stroke
o Huntington’s disease
o Multiple sclerosis (MS)
o Parkinson’s disease (PD)
o Prion diseases (e.g., Multiple system atrophy (MSA) or Creutzfeldt-Jakob disease (CJD))
o Any other neurological disorder (exception: migraine)
10. Psychiatric / psychological disorders
o Anxiety disorders (current diagnosis)
• Post-traumatic stress disorder
• Obsessive-compulsive disorder
• Any other anxiety disorder that significantly impacts day-to-day functioning (mild anxiety ok)
o Developmental disorders
• Autism spectrum disorder
• Attention-deficit / hyperactivity disorder (ADHD) (a.k.a. attention deficit disorder)
• Dyslexia (or Specific Learning Disorder (SLD) with reading difficulties)
• Any other learning disorder
o Impulse control disorder
o Mood disorder (current diagnosis)
• Bipolar disorder (a.k.a manic-depressive disorder)
• Major depression
• Any other form of depression
o Personality disorder
o Schizophrenia
11. Sleep apnoea
12. Substance use/abuse

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Cognitive function assessed using the Digit Span Backwards test, [At baseline and at two year post-enrollment];Brain health assessed using Magnetic Resonance Imaging (MRI) - structural brain connectivity[At baseline and at two year post-enrollment];Brain health assessed using Magnetic Resonance Imaging (MRI) - white matter hyperintensities. [At baseline and at two year post-enrollment]