NCT01285375Unknown1 期
Safety and Preliminary Efficacy of the Treatment of Kidney Allografts With Curcumin-containing Preservation Solution
适应症
试验速览
- 阶段
- 1 期
- 入组人数
- 20
- 试验地点
- 2
- 主要终点
- Delayed Graft Function
研究概览
简要总结
The safety and preliminary efficacy of the addition of an aqueous curcumin-cyclodextrin complex (CDC) solution to graft perfusion solution is studied. CDC has proved safe and highly effective in preventing primary graft non-function, delayed graft function and chronic dysfunction in pre-clinical kidney transplantation animal models. The hypothesis is that addition of CDC to the graft perfusion solution will decrease the incidence of delayed graft function in human kidney transplantation subjects.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with ESRD assigned for kidney transplantation, written informed consent
排除标准
- 未提供
结局指标
主要结局
Delayed Graft Function
时间窗: 7 days
次要结局
- Graft function eGFR(30 days, 90 days)
- Primary non-function(1 year)
- Acute rejection(1 year)
- Graft Survival(1 year)
- Patient Survival(1 year)
- Length of stay in hospital(upto 1 year)
研究者
研究点 (2)
Loading locations...
相似试验
Unknown
1 期
A Open-label Prospective Cohort Trial of Curcumin Plus Tyrosine Kinase Inhibitors (TKI) for EGFR -Mutant Advanced NSCLCLung CancerNCT02321293Lady Davis Institute20
已完成
1 期
A phase I/IIa study combining curcumin (Curcumin C3 Complex, Sabinsa) with standard care FOLFOX chemotherapy in patients with inoperable colorectal cancerCancerISRCTN58705307niversity of Leicester (UK)28
已完成
不适用
A study on the safety and efficacy of cyclodextrin intrathecal administration in Niemann-Pick disease type Ciemann-Pick disease type CJPRN-UMIN000023094ara Medical University1
尚未招募
不适用
A study on the efficacy and safety of cyclodextrin intrathecal long-term administration for Niemann-Pick disease type Ciemann-Pick disease type CJPRN-UMIN000023517ara Medical University1
已完成
2 期
Curcumin's Effect on Diabetic Patients With Atherosclerotic Cardiovascular RiskDyslipidemiasHypertensionDiabetes Mellitus, Type 2NCT05753436Ain Shams University72