MedPath

Dailies Total 1 Sphere Contact Lenses

Not Applicable
Completed
Conditions
Dry Eye
Contact Lens Complication
Interventions
Device: DT1 Sphere Contact Lenses
Registration Number
NCT05239494
Lead Sponsor
University of Alabama at Birmingham
Brief Summary

CL discomfort is a complex phenomenon that has been defined by the Tear Film and Ocular Surface Society in their seminal report on contact lens (CL) discomfort as a condition that results in "episodic or persistent adverse ocular sensation related to lens wear, either with or without visual disturbance resulting from reduced compatibility between the CL and the environment, which can lead to decreased wearing time and discontinuation of CL wear." A recent review by Pucker and Tichenor found that CL discomfort was the top reason for established CL wears to cease wearing CLs. This same review alarmingly found that the frequency of CL dropout was about 20% across the many studies aimed at evaluating this condition, which is surprising given the introduction of better soft CL materials and daily disposable CLs over the past 20 plus years.

Dailies Total1 (DT1), which is a relatively new daily disposable CL, is a commonly used trouble shooting CL for patients who have failed with other CLs because DT1 utilizes advanced material technology that is specifically aimed at improving CL comfort. While DT1 is commonly used in these struggling patients, the literature currently lacks a targeted study aimed at understanding the frequency of successfully refitting CL dropouts into this advanced CL. Thus, the purpose of this study is to determine the frequency that past CL wearers who failed because of dryness or CL discomfort who can comfortable wear DT1.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
60
Inclusion Criteria
  • Adults 18-40
  • Past contact lens wearers who have best corrected 20/20 visual acuity or better
  • Participants will have had to have worn contact lenses for at least 1 year in the past
  • Dropped out of contact lenses in the past 2 years do to discomfort or dryness
  • Scores of 3 or less on the SPEED questionnaire
  • Be able to be refit into Dailies Total1 Sphere contact lenses
  • Provide a glasses prescription that is less than 3-years-old
Exclusion Criteria
  • Past rigid contact lens wearers
  • A past history of being diagnosed with dry eye or ocular allergies
  • Known systemic health conditions that are known to alter tear film physiology
  • History of viral eye disease
  • History of ocular surgery
  • History of severe ocular trauma
  • History of corneal dystrophies or degeneration
  • Having active ocular infection or inflammation
  • Currently using isotretinoin-derivatives or ocular medication
  • Pregnant or breast feeding

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
Dailies Total1DT1 Sphere Contact LensesAll participants will be asked to wear Dailies Total1 for the duration of this study.
Primary Outcome Measures
NameTimeMethod
Visual Analog Scale (VAS) Contact Lenses Comfort Scores1 month

The median visual analog scale (VAS) scores at the 1-month visit (-50 to +50 scale with scores greater than 0 being comfortable).

Secondary Outcome Measures
NameTimeMethod
Likert QuestionnaireOne Month

Number of participants who were likely to refer the study contact lens to a friend.

Trial Locations

Locations (4)

Kannarr Eye Care

🇺🇸

Pittsburg, Kansas, United States

University of Alabama at Birmingham

🇺🇸

Birmingham, Alabama, United States

ProCare Vision Center

🇺🇸

Granville, Ohio, United States

The Southern College of Optometry

🇺🇸

Memphis, Tennessee, United States

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