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Bevacizumab therapy for retinopathy of prematurity

Not Applicable
Conditions
Intraocular neovascularization
Registration Number
JPRN-jRCTs051180175
Lead Sponsor
Ohnaka Masayuki
Brief Summary

Bevacizumab therapy was considered to be a safe and effective treatment for retinopathy of prematurity, because there were no complications after the treatment and the timing of retinal photocoagulation was able to push off.

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
21
Inclusion Criteria

1, Patients with diseases in which intraocular neovascular vessels do not disappear or reappeared after conventional therapy such as retinal photocoagulation
2, Retinopathy of prematurity, regardless of treatment, is zone I disease, zone II disease with stage 2+ or 3+, and aggressive posterior retinopathy of prematurity in the international classification
3, From 2 weeks old to 12 years old
4, Written informed consent by parents

Exclusion Criteria

1, Patients with infarct disease, heart failure with poor control, hypertension, renal failure, abnormal blood coagulation ability, gastrointestinal ulcer
2, Patients who need to take other treatment priorities due to poor general condition
3. Patients who judged that neonatal specialists, pediatricians or the researcher are inappropriate as research subjects
4. Patients participating in other studies

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Incidence of retinal detachment after treatment
Secondary Outcome Measures
NameTimeMethod
Incidence of cataract after treatment<br>Timing of retinal photocoagulation after treatment
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