Structured Stroke Management Improves Outcome at 6 Months
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 主要终点
- Mortality, dependence, psychoscial outcome
研究概览
简要总结
Background/Aim of the study: To further reduce the 6 months stroke morbidity and mortality in a high volume stroke hospital and to compare the results with national and international data.
Methods: 204 consecutive stroke patients are analyzed in a prospective study in a single center teaching institution. The intervention consists of a structured therapeutic chain of 290 collaborating GPs, a standardised acute hospital proceeding overlapping with an early integrated neurovascular rehabilitation within the same institution. Primary endpoints include death and dependence at 6 months, secondary endpoints are the length of hospital stay (LOS) and the quantitative analysis of physical and psychosocial impairments. The data are directly compared with the same endpoints of the Swiss subgroup of the international stroke trial (IST).
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •An acute cerebrovascular event (ischemic stroke or intra-cerebral bleeding (ICB)) with the signs and symptoms of an acute stroke according to the World Health Organisation definition of acute stroke14 within the last 12 hours without the need or possibility of a neurosurgical intervention
- •No thrombolytic therapy within the first 3 hours (in order to allow the correct comparison with the Swiss cohort of the IST trial
- •The informed consent of the patient or, if not possible, of the relatives
- •Living at home before the event
- •Lack of participation in another trial.
排除标准
- •Thrombolytic therapy within the first 3 hours (in order to allow the correct comparison with the Swiss cohort of the IST trial
- •No informed consent of the patient or, if not possible, of the relatives
- •Not living at home before the event
- •Participation in another trial (26 patients were excluded because of TIA with full recovery within 24 hours after the event)
结局指标
主要结局
Mortality, dependence, psychoscial outcome
Mortality, dependence and psychosocial outcome
时间窗: 6 months endpoint
次要结局
未报告次要终点