The incidence and risk factors of post-extubation dysphagia in critically ill surgical patients

Phase 1

• Conditions: neck radiation/surgery and who underwent tracheostomyThe common consequences of PED include pulmonary aspiration leading to aspiration pneumonia, an increase in reintubation rate, inadequate nutritional support, prolong duration of feeding tube with delayed reinstitution of oral feeding, a prolonged ICU and hospital stay, a decrease in the quality of life.; water swallowing test (WST); post-extubation dysphagia; Post-Extubation Dysphagia (PED) is a common condition in critically ill patients who admitted in the ICU. The occurrence is about 41% with some studies reported vary widely from 3% to 83%. It occurs frequently in patients who have high risks such as elderly patients, preexisting dysphagia, prolong intubation with mechanical ventilation (more than 48 hours), stroke and neurological problems, renal failure, cervical spine or head & fiberoptic endoscopic evaluation of swallowing (FEES)

• Registration Number: TCTR20211023003
• Lead Sponsor: Faculty of Medicine, Siriraj hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-10-23
• Study Completion: 2023-08-01
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: nknown
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

1.Age of 60 years old or more
2.Surgical ICU patients who were intubated and on mechanical ventilation for at least 48 hours after intubation
3.Successfully extubation
4.Stable hemodynamics (MAP more than 65 mmHg) without vasopressors use at the time of enrollment
5.Patient is awake, alert, and able to follow commands

Exclusion Criteria

1.Surgical procedure involving head and neck, cervical, cranial trauma, cardiothoracic surgery, neurosurgery
2.Surgical procedure involving GI tract that need to NPO more than 7 days
3.Tracheostomy
4.Profound deafness
5.Pre-existing dysphagia before underwent surgical procedure from other diseases e.g., neurological conditions: previous stroke, Parkinson disease, head& neck cancer, underwent head and neck surgery

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Dysphagia 28 day water swallowing test, FEES

Secondary Outcome Measures

Name	Time	Method
risk factors 28 day occurring