Prevalence, incidence and adherence of difficult-to-treat” adult asthma in the Netherlands.
Recruiting
- Conditions
- prevalenceadherencedifficult-to-treat asthmainhalation techniqueinhaled corticosteroidsPrevalentietherapietrouwastmainhalatietechniekcorticosteroiden
- Registration Number
- NL-OMON26986
- Lead Sponsor
- Academic Medical Centre, Amsterdam
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 1500
Inclusion Criteria
1. All patients using inhaled corticosteroids for at least 3 months at least one receipt repeated;
2. Patients from study 1 using fluticasone equivalent of ≥1000 µg or ≥ 500µg fluticasone equivalent per day + maintenance of 5mg prednisone per day for at least 30 days;
Exclusion Criteria
COPD.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. The prevalence and incidence of patients with difficult-to-treat asthma in the Netherlands;<br /><br>2. Factors associated with adherence to pulmonary medication in difficult-to-treat asthma;<br /><br>3. Primary: Inhalation technique scores in adherent patients with difficult-to-treat asthma;<br /><br>4. Primary: The proportion of patients with truly severe asthma (i.e. uncontrolled asthma or oral corticosteroid dependent asthma despite good adherence with high dose ICS and adequate inhalation technique).
- Secondary Outcome Measures
Name Time Method 1. Primary: Inhalation technique scores in adherent patients with difficult-to-treat asthma;<br /><br>2. Secondary: Factors associated with adequate or poor inhalation technique;<br /><br>4. Primary: The proportion of patients with truly severe asthma (i.e. uncontrolled asthma or oral corticosteroid dependent asthma despite good adherence with high dose ICS and adequate inhalation technique);<br /><br>4. Secondary: Factors associated with controlled or uncontrolled severe, refractory asthma.