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Clinical Trials/NCT05775276
NCT05775276Not yet recruitingNot Applicable

Incidence Of Mesh Infection After Hernioplasty In Obstructed and Strangulated Hernia Using Proline Mesh and Sutures

Assiut University0 sites60 target enrollmentStarted: March 1, 2023Last updated:
Conditions
Interventions

Trial Snapshot

Phase
Not Applicable
Status
Not yet recruiting
Enrollment
60
Primary Endpoint
Incidence Of Mesh Infection After Hernioplasty In Complicated Hernia Using Proline Mesh and Sutures

Study Overview

Brief Summary

The primary aim of this study is to detect incidence of mesh infection in cases presented with obstructed or strandulated hernia.A prospective controlled study will be carried out after obtaining written informed consent from all patients and approval of the ethics committee of the faculty of medicine, Assuit University.

Detailed Description

There is controversy regarding the use of prolene mesh in cases of obstructed and strangulated hernia. The main aim and objective of this prospective study is to evaluate the outcomes and incidence of mesh infection in hernioplasty in emergency situations like obstructed and strangulated hernia .Hernioplasty is the most common surgery for hernia repair with Propylene mesh,but the use of synthetic prosthesis is associated with increase risk of developing a prosthetic infection that may manifest after time as subtle symptoms in the form of fever, myalgia, erythema of overlying skin and in some cases as chronic discharging sinus(1). clinicians have been challenged in the past few years by an increasing variety of novel non-infectious and infectious complications following the widespread use of meshes after open repair of hernias this incidence is influenced by underlying co-morbidities, the type of mesh, the surgical technique and the strategy used to prevent infections. An approach that combines medical and surgical management is necessary for cases of mesh infection.(2)

Study Design

Study Type
Interventional
Allocation
Na
Intervention Model
Single Group
Primary Purpose
Screening
Masking
None

Eligibility Criteria

Ages
21 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • •All adult patients aging above 21 years old, who presented with obstructed or strangulated hernia with viable bowel loops by clinical examination or detected by preoperative ultrasound or computed tomography CT imaging.

Exclusion Criteria

  • •Uncomplicated hernia.
  • •patients who will underwent rescection and anastmosis
  • •patient cannot withstand anethesia.
  • •Decompensated liver patients.
  • •Pregnancy.
  • •Immunosuppressed patients e.g.: under chemotherapy or steroids.

Arms & Interventions

Incidence Of Mesh Infection After proline mesh Hernioplasty

Experimental

Cases presented with strangulated or obstructed hernia

Intervention: Proline mesh in hernioplasty (Procedure)

Outcomes

Primary Outcomes

Incidence Of Mesh Infection After Hernioplasty In Complicated Hernia Using Proline Mesh and Sutures

Time Frame: Baseline

To evaluate the incidence of mesh infection in Complicated hernia using prolene mesh and sutures,along postoperative hospital stay, routine follow up and time to return to activities of daily living.

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Mohamed Ashraf Abdelnaeem

Principal Investigator

Assiut University

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