The Ventilation During In-Hospital Cardiac Arrest (VENT-IHCA) Study
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 900
- 试验地点
- 21
- 主要终点
- Fraction of patients with return of spontaneous circulation (ROSC)
研究概览
简要总结
The goal of this prospective observational study is to learn how ventilation quality parameters during cardiopulmonary resuscitation (CPR) are associated with short-term survival following in-hospital cardiac arrest of adult patients.
The main questions it aims to answer are:
What ventilation volume during CPR is associated with the highest chance of return of spontaneous circulation (ROSC)? What ventilation rate during CPR is associated with the highest chance of ROSC?
Researchers will compare different levels of ventilation rates and volumes that are blindly measured during CPR to see how the observed rates and volumes are associated with survival outcomes and complications.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •In-hospital cardiac arrest
- •Age ≥ 18 years
- •>1minute of recorded ventilation data
排除标准
- •Documented do-not-attempt cardiopulmonary resuscitation order
- •Invasive mechanical circulatory support at the time of the cardiac arrest
研究组 & 干预措施
Study cohort
Adult patients (≥18 years) with in-hospital cardiac arrest receiving cardiopulmonary resuscitation.
Groups will be defined based on observed distribution of ventilation parameters (ventilation rate, tidal volume and minute ventilation).
干预措施: Positive pressure ventilation during cardiopulmonary resuscitation (Other)
结局指标
主要结局
Fraction of patients with return of spontaneous circulation (ROSC)
时间窗: ROSC is assessed immediately following cardiopulmonary resuscitation.
ROSC is defined as sustained spontaneous circulation with no need for chest compressions for at least 20 minutes.
次要结局
- Fraction of patients surviving until day 30(Assessed at day 30 after cardiac arrest.)