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Clinical Trials/NCT07703683
NCT07703683RecruitingNot Applicable

Myokines as Potential Biomarkers and Drivers of Sarcopenia in Metabolic and Endocrine Diseases

Cliniques universitaires Saint-Luc- Université Catholique de Louvain1 site in 1 country100 target enrollmentStarted: February 19, 2026Last updated:
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Conditions
Drugs

Trial Snapshot

Phase
Not Applicable
Status
Recruiting
Sponsor
Enrollment
100
Locations
1
Primary Endpoint
Prevalence of sarcopenia / sarcopenic obesity
Study OverviewStudy DesignEligibility CriteriaOutcomesInvestigatorsSitesRecords & IdentifiersSimilar Trials

Study Overview

Brief Summary

Prospective, observational, single-center, study evaluating the prevalence of sarcopenia / sarcopenic obesity in individuals with metabolic and / or endocrine diseases, as well as the potential role of myokines as biomarkers or drivers of sarcopenia / sarcopenic obesity in this population.

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Study Design

Study Type
Observational
Observational Model
Cohort
Time Perspective
Prospective

Eligibility Criteria

Ages
18 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • •Metabolic or endocrine disease

Exclusion Criteria

  • •Known myopathy
  • •Systemic steroid use (> 1 mg/kg hydrocortisone) or exogenous Cushing's syndrome
  • •Psychological, family, sociological or geographical conditions that could potentially limit compliance with the study protocol
  • •History of cancer within the five years prior to the study or Cushing's syndrome due to ACTH-secreting tumor

Outcomes

Primary Outcomes

Prevalence of sarcopenia / sarcopenic obesity

Time Frame: From February 2026 to december 2056

Secondary Outcomes

  • Prevalence of MASLD(March 2026 to December 2056)
  • Prevalence of MASH(March 2026 to December 2056)
  • Myokines levels in serum or plasma(February 2026 to December 2056)
  • Myokine expression(February 2026 to December 2056)

Investigators

Sponsor
Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Sponsor Class
Other
Responsible Party
Sponsor

Study Sites (1)

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