跳至主要内容
临床试验/NCT07703683
NCT07703683招募中不适用

Myokines as Potential Biomarkers and Drivers of Sarcopenia in Metabolic and Endocrine Diseases

Cliniques universitaires Saint-Luc- Université Catholique de Louvain1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2026年2月19日最近更新:
适应症
相关药物

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
100
试验地点
1
主要终点
Prevalence of sarcopenia / sarcopenic obesity

研究概览

简要总结

Prospective, observational, single-center, study evaluating the prevalence of sarcopenia / sarcopenic obesity in individuals with metabolic and / or endocrine diseases, as well as the potential role of myokines as biomarkers or drivers of sarcopenia / sarcopenic obesity in this population.

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研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Metabolic or endocrine disease

排除标准

  • Known myopathy
  • Systemic steroid use (> 1 mg/kg hydrocortisone) or exogenous Cushing's syndrome
  • Psychological, family, sociological or geographical conditions that could potentially limit compliance with the study protocol
  • History of cancer within the five years prior to the study or Cushing's syndrome due to ACTH-secreting tumor

结局指标

主要结局

Prevalence of sarcopenia / sarcopenic obesity

时间窗: From February 2026 to december 2056

次要结局

  • Prevalence of MASLD(March 2026 to December 2056)
  • Prevalence of MASH(March 2026 to December 2056)
  • Myokines levels in serum or plasma(February 2026 to December 2056)
  • Myokine expression(February 2026 to December 2056)

研究者

发起方
Cliniques universitaires Saint-Luc- Université Catholique de Louvain
申办方类型
Other
责任方
Sponsor

研究点 (1)

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