Evaluating the effects of Vitamin K supplements on Aortic Stenosis
Not Applicable
Recruiting
- Conditions
- Calcific Aortic StenosisCardiovascular - Other cardiovascular diseasesCardiovascular - Diseases of the vasculature and circulation including the lymphatic system
- Registration Number
- ACTRN12622000447752
- Lead Sponsor
- niversity of Western Australia
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 108
Inclusion Criteria
1) Aged 18+ years
2) Mild to moderate calcific aortic stenosis (peak flow velocity greater than 2.5m/s and less than 4m/s)
3) Valve area greater than 1 cm2
4) At least mild aortic valve calcification (Rosenhek category=1) on echocardiography.
Exclusion Criteria
1) Planned procedure to unblock heart arteries
2) Clinically important disease of any heart valve
3) Kidney disease (eGFR<40ml/min)
4) Intolerance to Vitamin-K
5) Prescribed a Vitamin-K blocker or supplement
6) Heart rhythm disturbance preventing a good quality CT-calcium score scan
7) Pregnancy
8) Unlikely to complete the 12 months follow-up.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method