"A Comparative Clinical Evaluation of the Efficacy of Topical Adapalene, Benzoyl Peroxide Gel, Oral Lactobacillus Rhamnosus, D-chiro-inositol, Inulin Capsule, and Their Fixed Combination in Mild to Moderate Acne Vulgaris Patients."
Overview
- Phase
- Not Applicable
- Intervention
- Topical Adapalene, Benzoyl Peroxide Gel
- Conditions
- Acne Vulgaris
- Sponsor
- Treatment and Diagnostic Center of Private Enterprise "Asklepiy"
- Enrollment
- 59
- Locations
- 1
- Primary Endpoint
- GAGS (Global Acne Grading System)
- Status
- Active, not recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
The study aims to conduct a comparative clinical evaluation of the effectiveness of a fixed topical combination of adapalene with benzoyl peroxide in the form of a gel, a fixed combination of Lactobacillus rhamnosus, D-chiro-inositol and inulin in the form of capsules and their combination in patients with acne vulgaris of mild and moderate severity and laboratory lipid analysis profile of sebum, lipid metabolism, and IGF-1 (insulin-like growth factor).
Investigators
Yuriy Andrashko
Yuriy Andrashko
Treatment and Diagnostic Center of Private Enterprise "Asklepiy"
Eligibility Criteria
Inclusion Criteria
- •Patients with mild to moderate level of Acne Vulgaris
Exclusion Criteria
- •Pregnancy
Arms & Interventions
Topical Adapalene, Benzoyl Peroxide Gel
Intervention: Topical Adapalene, Benzoyl Peroxide Gel
Oral Lactobacillus Rhamnosus, D-chiro-inositol, Inulin Capsule
Intervention: Oral Lactobacillus Rhamnosus, D-chiro-inositol, Inulin Capsule
Topical Adapalene,Benzoyl Peroxide Gel,Oral Lactobacillus Rhamnosus,D-chiro-inositol,Inulin Capsule
Intervention: Oral Lactobacillus Rhamnosus, D-chiro-inositol, Inulin Capsule
Topical Adapalene,Benzoyl Peroxide Gel,Oral Lactobacillus Rhamnosus,D-chiro-inositol,Inulin Capsule
Intervention: Topical Adapalene, Benzoyl Peroxide Gel
Outcomes
Primary Outcomes
GAGS (Global Acne Grading System)
Time Frame: 180 days
The primary end point of the study is the intensity of acne manifestations according to the GAGS scale
Secondary Outcomes
- IGA (Investigator Global Assessment)(180 days)