"A Comparative Clinical Evaluation of the Efficacy of Topical Adapalene, Benzoyl Peroxide Gel, Oral Lactobacillus Rhamnosus, D-chiro-inositol, Inulin Capsule, and Their Fixed Combination in Mild to Moderate Acne Vulgaris Patients."
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 59
- 试验地点
- 1
- 主要终点
- GAGS (Global Acne Grading System)
研究概览
简要总结
The study aims to conduct a comparative clinical evaluation of the effectiveness of a fixed topical combination of adapalene with benzoyl peroxide in the form of a gel, a fixed combination of Lactobacillus rhamnosus, D-chiro-inositol and inulin in the form of capsules and their combination in patients with acne vulgaris of mild and moderate severity and laboratory lipid analysis profile of sebum, lipid metabolism, and IGF-1 (insulin-like growth factor).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 27 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients with mild to moderate level of Acne Vulgaris
排除标准
- •Pregnancy
研究组 & 干预措施
Topical Adapalene, Benzoyl Peroxide Gel
干预措施: Topical Adapalene, Benzoyl Peroxide Gel (Drug)
Oral Lactobacillus Rhamnosus, D-chiro-inositol, Inulin Capsule
干预措施: Oral Lactobacillus Rhamnosus, D-chiro-inositol, Inulin Capsule (Dietary Supplement)
Topical Adapalene,Benzoyl Peroxide Gel,Oral Lactobacillus Rhamnosus,D-chiro-inositol,Inulin Capsule
干预措施: Oral Lactobacillus Rhamnosus, D-chiro-inositol, Inulin Capsule (Dietary Supplement)
Topical Adapalene,Benzoyl Peroxide Gel,Oral Lactobacillus Rhamnosus,D-chiro-inositol,Inulin Capsule
干预措施: Topical Adapalene, Benzoyl Peroxide Gel (Drug)
结局指标
主要结局
GAGS (Global Acne Grading System)
时间窗: 180 days
The primary end point of the study is the intensity of acne manifestations according to the GAGS scale
次要结局
- IGA (Investigator Global Assessment)(180 days)
研究者
Yuriy Andrashko
Yuriy Andrashko
Treatment and Diagnostic Center of Private Enterprise "Asklepiy"