Secondary Manifestations of ARTerial diseases in the Young with a chronic conditio

• Conditions: atherosclerosis; cardiovascular disease; 10003216

• Registration Number: NL-OMON56581
• Lead Sponsor: niversitair Medisch Centrum Utrecht

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 9 April 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 1350

Inclusion Criteria

Inclusion criteria for SMART-Youth consist of children aged 8 to 18 years with
various chronic conditions recruited from the PROactive cohort. The study will
include the following chronic conditions: cystic fibrosis, juvenile idiopathic
arthritis, systemic autoimmune diseases, chronic kidney disease, primary
immunodeficiency, autoinflammatory conditions, inflammatory bowel disease, and
congenital heart disease, as well as children with a history of premature birth
or fetal growth restriction , and children with unexplained medical symptoms.
Children with a history of premature birth or fetal growth restriction are
planned to be included in the PROactive cohort soon.

Exclusion Criteria

There are no exclusion criteria.

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Carotid Intima Media Thickness (cIMT) and Aortic pulse wave velocity (PWV), and<br /><br>it's development over time as preclinical atherosclerosis outcomes.</p><br>