NL-OMON26950招募中不适用
A randomized phase II study for evaluation of T cell depleted non myeloablative allogeneic stem cell transplantation followed by early consolidation with lenalidomide or lenalidomide combined with bortezomib and subsequent DLI for patients with multiple myeloma in progression or relapse following first line therapy.
Stichting Hemato-Oncologie voor Volwassenen Nederland (HOVON) P/a HOVON Data CenterErasmus MC - Daniel den HoedPostbus 52013008 AE RotterdamTel: 010 7041560Fax: 010 7041028e-mail: hdc@erasmusmc.nl0 个研究点目标入组 110 人开始时间: 待定最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 110
研究概览
简要总结
/A
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •1. Patients with multiple myeloma with a first relapse or progression after first line therapy;
- •2. Relapsed or progressive patients have received reinduction therapy before entering this trial;
排除标准
- •1. Previous Allo-SCT;
- •2. Severe pulmonary dysfunction (CTCAE grade III-IV, see appendix D);
研究者
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A study of the effect of donor stem cell transplantation followed by treatment with lenalidomide or lenalidomide with bortezomib and subsequent DLI for patients with a relapse or progression following first line therapyPatients, 18-65 years, inclusive, multiple myeloma with a first relapse or progression after first line therapy (with a HLA- identical sibling or unrelated donor completely matched (10/10))MedDRA version: 14.1Level: PTClassification code 10028228Term: Multiple myelomaSystem Organ Class: 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)EUCTR2010-018494-37-NLHOVON Foundation
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