Effects of Agility Training on Executive Function, Dual Task Performance and Brain Activation in Healthy Adults
Trial Snapshot
- Phase
- Not Applicable
- Enrollment
- 70
- Locations
- 1
- Primary Endpoint
- Executive function- N-back task (3-back)
Study Overview
Brief Summary
This study will investigate the effect of agility training on executive function, dual task walking and brain activation in healthy adults. Participants (N=70) will be randomly assigned to resistance+aerobic training group (RAeT) or agility training group (AT). Participants in RAeT (n=35) will receive 15-minute lower extremity workout first and then 25-minute moderate intensity (60-75% predicted maximal heart rate) aerobic training. Participants in AT (n=35) will do the agility exercise program consisting of technical drills, pattern running and reactive agility training. The intervention will be twelve-time group intervention (3-5persons) in four weeks, 50 minutes per session (5-minute warmup, 40- minute main training, 5-minute cool-down). Participants will undergo three measurement time points (pre-, post-intervention and one month follow-up). Outcome measures will include executive function (N-back test, stroop test and Wisconsin card sort test), single and dual task walking performance and brain activity (fNIRS on prefrontal cortex, supplementary motor area and premotor cortex). Two-way analysis of variance (ANOVA) with Tukey post-hoc test will be used to examine the group x time interaction on three outcome measures.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Single (Participant)
Eligibility Criteria
- Ages
- 20 Years to 30 Years (Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •(1) age between 20 to 30 years, and (2) ability to walk 20 meters independently without an assistive device.
Exclusion Criteria
- •(1) overweight (BMI>24), (2) any smoker or alcohol abusers, (3) suffering from chronic diseases that loss of control, (4) Unstable physiological conditions, such as abnormal signs like high blood pressure, headache, dyspnea, fever, etc., (5) any neuromuscular or cardiopulmonary diseases that would influent the exercise performance, and (6) suffering from diseases which exercises are their contraindications
Arms & Interventions
Resistance+Aerobic training group
Resistance+Aerobic training group (RAeT) RAeT includes resistance training (RT) program and aerobic training (AeT) program.
Intervention: Resistance+Aerobic training (Other)
Agility training group
Agility training
Intervention: Agility training (Other)
Outcomes
Primary Outcomes
Executive function- N-back task (3-back)
Time Frame: Change from Baseline score at 7 weeks
N-back task (3-back) is used to measure working memory
Single walking performance- Cadence
Time Frame: Change from Baseline cadence at 7 weeks
The unit is steps per minutes
Single walking performance- Stride length
Time Frame: Change from Baseline cadence at 7 weeks
The unit is cm
Dual task walking performance- Cadence
Time Frame: Change from Baseline cadence at 7 weeks
The unit is steps per minutes
Dual task walking performance- the correct rates of arithmetic task
Time Frame: Change from Baseline cadence at 7 weeks
The participants will be instructed to subtract by 7 serially from a 3-digit number while walking at their fastest speed in dual task walking condition
Executive function- Stroop test
Time Frame: Change from Baseline score at 7 weeks
Stroop test is used to measure the selective attention and conflict resolution.
Single walking performance- Walking speed
Time Frame: Change from Baseline cadence at 7 weeks
The unit is length (cm) per seconds
Dual task walking performance- Stride length
Time Frame: Change from Baseline cadence at 7 weeks
The unit is cm
Dual task walking performance- Step duration
Time Frame: Change from Baseline cadence at 7 weeks
The unit is seconds
Executive function- Wisconsin card sort test
Time Frame: Change from Baseline score at 7 weeks
Wisconsin card sort test is an easy way to assess the ability of mental set shifting.
Single walking performance- Step duration
Time Frame: Change from Baseline cadence at 7 weeks
The unit is seconds
Dual task walking performance- Walking speed
Time Frame: Change from Baseline cadence at 7 weeks
The unit is length (cm) per seconds
Single walking performance- Walking speed
Time Frame: Change from Baseline cadence at 3 weeks
The unit is length (cm) per seconds
Executive function- N-back task (3-back)
Time Frame: Change from Baseline score at 3 weeks
N-back task (3-back) is used to measure working memory
Executive function- Stroop test
Time Frame: Change from Baseline score at 3 weeks
Stroop test is used to measure the selective attention and conflict resolution.
Executive function- Wisconsin card sort test
Time Frame: Change from Baseline score at 3 weeks
Wisconsin card sort test is an easy way to assess the ability of mental set shifting.
Single walking performance- Cadence
Time Frame: Change from Baseline cadence at 3 weeks
The unit is steps per minutes
Single walking performance- Stride length
Time Frame: Change from Baseline cadence at 3 weeks
The unit is cm
Single walking performance- Step duration
Time Frame: Change from Baseline cadence at 3 weeks
The unit is seconds
Dual task walking performance- Walking speed
Time Frame: Change from Baseline cadence at 3 weeks
The unit is length (cm) per seconds
Dual task walking performance- Cadence
Time Frame: Change from Baseline cadence at 3 weeks
The unit is steps per minutes
Dual task walking performance- Stride length
Time Frame: Change from Baseline cadence at 3 weeks
The unit is cm
Dual task walking performance- Step duration
Time Frame: Change from Baseline cadence at 3 weeks
The unit is seconds
Dual task walking performance- the correct rates of arithmetic task
Time Frame: Change from Baseline cadence at 3 weeks
The participants will be instructed to subtract by 7 serially from a 3-digit number while walking at their fastest speed in dual task walking condition
Secondary Outcomes
- Brain activities over supplementary motor area- Single walking(Change from Baseline at 7 weeks)
- Brain activities over premotor cortex- Dual task walking(Change from Baseline at 7 weeks)
- Brain activities over premotor cortex- Executive function(Change from Baseline at 7 weeks)
- Brain activities over supplementary motor area- Dual task walking(Change from Baseline at 7 weeks)
- Brain activities over supplementary motor area- Executive function(Change from Baseline at 7 weeks)
- Brain activities over primary motor cortex - Single walking(Change from Baseline at 7 weeks)
- Brain activities over primary motor cortex - Dual task walking(Change from Baseline at 7 weeks)
- Brain activities over primary motor cortex- Executive function(Change from Baseline at 7 weeks)
- Brain activities over premotor cortex- Single walking(Change from Baseline at 7 weeks)
- Brain activities over premotor cortex- Executive function(Change from Baseline at 3 weeks)
- Brain activities over supplementary motor area- Executive function(Change from Baseline at 3 weeks)
- Brain activities over primary motor cortex- Executive function(Change from Baseline at 3 weeks)
- Brain activities over premotor cortex- Single walking(Change from Baseline at 3 weeks)
- Brain activities over supplementary motor area- Single walking(Change from Baseline at 3 weeks)
- Brain activities over primary motor cortex - Single walking(Change from Baseline at 3 weeks)
- Brain activities over premotor cortex- Dual task walking(Change from Baseline at 3 weeks)
- Brain activities over supplementary motor area- Dual task walking(Change from Baseline at 3 weeks)
- Brain activities over primary motor cortex - Dual task walking(Change from Baseline at 3 weeks)