Evaluation of the Effect of Zingiber Officinalis on Nausea and Vomiting in Patients Receiving Cisplatin Based Regimens
Not Applicable
Completed
- Conditions
- NauseaVomiting
- Interventions
- Dietary Supplement: GingerDietary Supplement: Placebo
- Registration Number
- NCT00537875
- Lead Sponsor
- National Research Institute of Tuberculosis and Lung Disease, Iran
- Brief Summary
The purpose of this study is to determine whether powdered ginger root (encapsulated ginger) is effective for reducing the frequency, duration and severity of both acute and delayed nausea and vomiting.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 36
Inclusion Criteria
- Must be able to give written informed consent.
- Have a diagnosis of cancer and currently receiving chemotherapy containing cisplatin (any dose).
- Scheduled to receive antiemetics: granisetron (kytril), hydrocortisone.
- Must be able to complete study questionnaires.
- Must be able to swallow capsules.
Exclusion Criteria
- Have no clinical evidence of current or impending bowel obstruction.
- Concurrent radiotherapy that is classified as high or intermediate risk of causing emesis.
- Pregnant or lactating.
- Patients taking therapeutic doses of coumadin (individuals on low-dose to maintain peripheral or central venous catheters are allowed), aspirin (individuals taking low-dose 80mg aspirin are allowed), or heparin.
- Patients with a history of a bleeding disorder(s) in past 6 months and those experiencing thrombocytopenia.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Arm && Interventions
Group Intervention Description 1 Ginger - 2 Placebo -
- Primary Outcome Measures
Name Time Method Nausea, Vomiting 3 days
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
National Research Institute of Tuberculosis and Lung Disease (NRITLD)
🇮🇷Tehran, Iran, Islamic Republic of