Silent Breast Cancer A Study of the Disease Prevalence Held by Imaging Guided Biopsies in Autopsy Specimens
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 768
- 主要终点
- Silent breast cancer prevalence
研究概览
简要总结
The aim of this study is to define silent breast cancer prevalence in both sexes and will be held by biopsies performed in imaging suspicious areas of the breast (ecography and mammography) in cadavers without known breast cancer.
详细描述
Cadavers of both sexes are going to be submitted to bilateral mastectomy. The specimens are going to be examined by palpation, ecography and mammography and all areas with (Breast Imaging Reporting and Data System) BI-RADS classification >= 3 are going to be biopsied.
Biopsy specimens are going to be processed by the pathology department and cancers are going to be identified and classified by their molecular type.
The investigators intend to know which is the disease reservoir in various ages.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 40 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Female and male cadavers above 40 years
排除标准
- •Known breast cancer
- •Breast tissue accidental damage
研究组 & 干预措施
female cadavers
female cadavers above 40 years without known breast cancer Bilateral mastectomy Biopsy
干预措施: Bilateral mastectomy (Procedure)
female cadavers
female cadavers above 40 years without known breast cancer Bilateral mastectomy Biopsy
干预措施: Biopsy (Other)
Male cadavers
male cadavers above 40 years without known breast cancer Bilateral mastectomy Biopsy
干预措施: Bilateral mastectomy (Procedure)
Male cadavers
male cadavers above 40 years without known breast cancer Bilateral mastectomy Biopsy
干预措施: Biopsy (Other)
结局指标
主要结局
Silent breast cancer prevalence
时间窗: 2 years
To define the existing disease that did not caused death in both sexes
次要结局
- Silent breast cancer prevalent molecular profile(2 years)
研究者
Zacharoula Sidiropoulou
Zacharoula Sidiropoulou MD, MSc, Principal Investigator, General Surgery Assistent
Centro Hospitalar Lisboa Ocidental