Fetal Heart Rate Variability Compared to Doppler Flows in the Growth Restricted Fetus: a Cohort Study
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Fetal Growth Retardation
- Sponsor
- University of Aarhus
- Enrollment
- 40
- Locations
- 1
- Primary Endpoint
- Low frequency power/High frequency power (LF/HF)
- Last Updated
- 5 years ago
Overview
Brief Summary
There is growing evidence in the field of fetal heart rate variability revealing the fetal neurological state. Furthermore, fetal heart rate variability has shown potential as fetal surveillance in fetal growth restriction.
This study aim to investigate the association between fetal heart rate variability and doppler flow changes in growth restricted fetuses.
Investigators
Eligibility Criteria
Inclusion Criteria
- •singleton pregnant women with estimated fetal weight below 2 standard deviations (2SD) of mean for gestational age corresponding to minus 22%. Fetal weight assessed by doppler ultrasound.
Exclusion Criteria
- •Fetal malformations
Outcomes
Primary Outcomes
Low frequency power/High frequency power (LF/HF)
Time Frame: 1/12-2020
Spectral analysis
Root mean square of successive inter beat interval differences RMSSD
Time Frame: 1/12-2020
Time domain analysis
Low frequency power (LF-power)
Time Frame: 1/12-2020
Spectral analysis
High frequency power (HF-power)
Time Frame: 1/12-2020
Spectral analysis
Standard deviation of normal to normal inter beat interval (SDNN)
Time Frame: 1/12-2020
Time domain analysis