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Fetal Heart Rate Variability and Fetal Growth Restriction

Conditions
Fetal Growth Retardation
Registration Number
NCT04288037
Lead Sponsor
University of Aarhus
Brief Summary

There is growing evidence in the field of fetal heart rate variability revealing the fetal neurological state. Furthermore, fetal heart rate variability has shown potential as fetal surveillance in fetal growth restriction.

This study aim to investigate the association between fetal heart rate variability and doppler flow changes in growth restricted fetuses.

Detailed Description

Not available

Recruitment & Eligibility

Status
UNKNOWN
Sex
Female
Target Recruitment
40
Inclusion Criteria
  • singleton pregnant women with estimated fetal weight below 2 standard deviations (2SD) of mean for gestational age corresponding to minus 22%. Fetal weight assessed by doppler ultrasound.
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Exclusion Criteria
  • Fetal malformations
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Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Low frequency power/High frequency power (LF/HF)1/12-2020

Spectral analysis

Root mean square of successive inter beat interval differences RMSSD1/12-2020

Time domain analysis

Low frequency power (LF-power)1/12-2020

Spectral analysis

High frequency power (HF-power)1/12-2020

Spectral analysis

Standard deviation of normal to normal inter beat interval (SDNN)1/12-2020

Time domain analysis

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Arhus Universityhospital

🇩🇰

Aarhus, Aarhus N, Denmark

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