Fetal Heart Rate Variability Compared to Doppler Flows in the Growth Restricted Fetus: a Cohort Study
试验速览
- 阶段
- 不适用
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Low frequency power/High frequency power (LF/HF)
研究概览
简要总结
There is growing evidence in the field of fetal heart rate variability revealing the fetal neurological state. Furthermore, fetal heart rate variability has shown potential as fetal surveillance in fetal growth restriction.
This study aim to investigate the association between fetal heart rate variability and doppler flow changes in growth restricted fetuses.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •singleton pregnant women with estimated fetal weight below 2 standard deviations (2SD) of mean for gestational age corresponding to minus 22%. Fetal weight assessed by doppler ultrasound.
排除标准
- •Fetal malformations
结局指标
主要结局
Low frequency power/High frequency power (LF/HF)
时间窗: 1/12-2020
Spectral analysis
Root mean square of successive inter beat interval differences RMSSD
时间窗: 1/12-2020
Time domain analysis
Low frequency power (LF-power)
时间窗: 1/12-2020
Spectral analysis
High frequency power (HF-power)
时间窗: 1/12-2020
Spectral analysis
Standard deviation of normal to normal inter beat interval (SDNN)
时间窗: 1/12-2020
Time domain analysis
次要结局
未报告次要终点