Virtual Exercise Intervention for Older Adults With MCI
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Oregon Research Institute
- Enrollment
- 69
- Locations
- 1
- Primary Endpoint
- Change in cognitive functioning assessed by Everyday Cognition
Study Overview
Brief Summary
This project is designed to develop and evaluate an Internet-based exercise intervention (tai ji quan Moving to Improve Brain Health) using real-time videoconferencing for older adults with mild cognitive impairment (MCI).
Detailed Description
The project has three major goals: (a) transforming an in-person tai ji quan brain health intervention protocol into an online (virtual) class protocol and evaluating its feasibility of implementation in older adults with MCI, (b) developing and evaluating online assessment and data ascertainment procedures that encompass cognitive and physical performance measures, and (c) conducting a randomized controlled trial comparing the effectiveness of this new online intervention protocol with a conventional stretching exercise group in older adults with MCI.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Prevention
- Masking
- Single (Outcomes Assessor)
Eligibility Criteria
- Ages
- 65 Years to 95 Years (Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Self-report a change or decline in memory (corroborated by an informant)
- •Record a score of ≤0.5 on the Clinical Dementia Rating (CDR) scale (with information derived from both the participant and an informant)
- •Show no major impairment in cognitive function as indexed by a score of ≥24 on the Mini Mental State Evaluation (MMSE).
Exclusion Criteria
- •Have participated in a rigorous and structured physical activity or exercise program (including Tai Ji Quan) in the past 6 months,
- •Show major signs of depression as indicated by a score of ≥5 on the Geriatric Depression Scale
- •Have major medical or physical conditions that preclude exercise, as determined by their healthcare practitioner
- •Being unable to follow the consent process or sign the study consent form.
Arms & Interventions
cognitively enhanced tai ji quan
Participants receive a cognitively enhanced tai ji quan exercise intervention for 16 weeks.
Intervention: tai ji quan (Behavioral)
stretching exercise
Participants receive a stretching exercise intervention for 16 weeks.
Intervention: Stretching (Behavioral)
Outcomes
Primary Outcomes
Change in cognitive functioning assessed by Everyday Cognition
Time Frame: baseline, 16 weeks
assess change from baseline cognitive functioning at 16 weeks
Change in attention and working memory as assessed by Digit Span - forward and backward
Time Frame: baseline, 16 weeks
assess change from baseline in attention and working memory at 16 weeks
Change in dual-task cost as assessed by Timed Up and Go with a cognitive task
Time Frame: baseline, 16 weeks
assess change from baseline in the ability to stand up from a chair, walk, and sit down while performing an arithmetic task at 16 weeks
Change in executive function as assessed by Trail Making B
Time Frame: baseline, 16 weeks
assess change from baseline executive function at 16 weeks
Change in executive function as assessed by Category Fluency for Animals
Time Frame: baseline, 16 weeks
assess change from baseline executive function at 16 weeks
number of dropouts from the intervention and study as assessed by a study recording sheet
Time Frame: 16 weeks
assess intervention dropout rate and retention rate
Number of participants expressing intervention program satisfaction as assessed by a self-report survey
Time Frame: 16 weeks
assess the program acceptability among tai ji quan participants
Change in global cognitive function assessed by Montreal Cognitive Assessment
Time Frame: baseline, 16 weeks
assess change from baseline cognitive function at 16 weeks
Change in balance using a 4-stage balance test
Time Frame: baseline, 16 weeks
assess change from baseline in balance at 16 weeks
Change in physical performance as measured by Timed Up and Go test
Time Frame: baseline, 16 weeks
assess change from baseline in the ability to stand up from a chair, walk, and sit down at 16 weeks
(a) Total number of intervention sessions taught by instructors over the course of study (recorded by a class check sheet) and (b) total number of classes attended by participants over the course of intervention as recorded by class attendance sheet
Time Frame: 16 weeks
assess the extent to which interventionists successfully implement the prespecified exercise training protocol.
change in leg strength as assessed by 30-second chair stand test
Time Frame: baseline, 16 weeks
assess change from baseline in leg strength at 16 weeks
Secondary Outcomes
- Change in quality of life as assessed by EuroQol (EQ-5D-3L)(baseline, 16 weeks)
- Change in depression as assessed by Geriatric Depression scale(baseline, 16 weeks)
- Change in physical activity as assessed by International Physical Activity Questionnaire(baseline, 16 weeks)